Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 18, Problem 13P
Summary Introduction

To analyze:

The bicoid is characterized as a coordinate, maternal effect gene. Based on this, answer the following:

Determine the phenotype of the progeny produced from the cross between female Drosophila heterozygous for a loss of function bicoid allele and male that is heterozygous for the same allele.

Determine the phenotype of progeny produced from a cross between a female that is homozygous for a loss of function bicoid allele and a wild type male.

Provide an explanation on, if losses of bicoid function in the egg results in lethality during embryogenesis how are females homozygous for bicoid produced. Also determine phenotype of a male homozygous for bicoid loss of function alleles.

Introduction:

Bicoid is an example of a maternal effect gene. The phenotype result from maternal effect gene is identified by the mother genotype and not by the organism phenotype. This is because the egg receives protein and mRNA needed for proper development from the mother for the determination and development of a body axis in an organism. Bicoid is essential, thus, it is also termed as axis determination gene.

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Drosophila, yellow body color is due to an X-linked gene that is recessive to the gene for gray body color.a. A homozygous gray female is crossed with a yellow male. The F1 are intercrossed to produce the F2. Give the genotypes and phenotypes, along with the expected proportions, of the F1 and F2 progeny.b. A yellow female is crossed with a gray male. The F1 are intercrossed to produce the F2. Give the genotypes and phenotypes, along with the expected proportions, of the F1 and F2 progeny.c. A yellow female is crossed with a gray male. The F1 females are backcrossed with gray males. Give the genotypes and phenotypes, along with the expected proportions, of the F2 progeny.d. If the F2 flies in part b mate randomly, what are the expected phenotypes and proportions of flies in the F3?
In Drosophila, an X-linked recessive mutation, (s) causes irregular wing margins. Give the genotypes, phenotypes and phenotypic ratio of the F1 and F2 offspring in the following crosses a. scalloped female crossed with a normal male b. scalloped male crossed with a homozygous normal female. Compare these results to those that would be obtained if the scalloped gene is autosomal.
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Genetic Analysis: An Integrated Approach (3rd Edition)

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