Microbiology with Diseases by Body System (4th Edition)
4th Edition
ISBN: 9780321918550
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 18, Problem 8CT
Retroviruses such as HIV use RNA as a primer for DNA synthesis. Why is a primer necessary?
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Chapter 18 Solutions
Microbiology with Diseases by Body System (4th Edition)
Ch. 18 - Prob. 1CCSCh. 18 - Prob. 1TMWCh. 18 - Prob. 2TMWCh. 18 - A Case of AIDS A 25-year-old man is admitted to...Ch. 18 - Prob. 3TMWCh. 18 - The immunoglobulin class that mediates type I...Ch. 18 - The major inflammatory mediator released by...Ch. 18 - Hemolytic disease of the new born is caused by...Ch. 18 - Farmers lung is a hypersensitivity pneumonitis...Ch. 18 - A positive tuberculin skin test indicates that a...
Ch. 18 - Which of the following is an autoimmune disease?...Ch. 18 - When a surgeon conducts a cardiac bypass operation...Ch. 18 - A deficiency of both B cells and T cells is most...Ch. 18 - Prob. 9MCCh. 18 - What do medical personnel administer to counteract...Ch. 18 - Which of the following is not typically part of an...Ch. 18 - Prob. 12MCCh. 18 - Prob. 13MCCh. 18 - Prob. 14MCCh. 18 - Prob. 15MCCh. 18 - Prob. 1MTFCh. 18 - Prob. 2MTFCh. 18 - Prob. 3MTFCh. 18 - Prob. 4MTFCh. 18 - Modified True/False 5. ___ Graft-versus-host...Ch. 18 - Prob. 1MCh. 18 - Prob. 1SACh. 18 - Prob. 2SACh. 18 - Prob. 3SACh. 18 - Contrast autografts, isografts, allografts, and...Ch. 18 - Prob. 5SACh. 18 - Prob. 1VICh. 18 - Prob. 2VICh. 18 - Prob. 3VICh. 18 - Prob. 1CTCh. 18 - Why cant physicians use skin tests similar to the...Ch. 18 - Prob. 3CTCh. 18 - Prob. 4CTCh. 18 - What types of illnesses cause death in patients...Ch. 18 - Prob. 6CTCh. 18 - Why do the blisters of positive tuberculin...Ch. 18 - Retroviruses such as HIV use RNA as a primer for...Ch. 18 - Prob. 9CTCh. 18 - Reverse transcriptase is notoriously sloppy in...Ch. 18 - A patient arrives at the doctors office with a...Ch. 18 - Prob. 12CTCh. 18 - Prob. 13CTCh. 18 - Prob. 1CM
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- Some retroviruses that have a wide host range have been developed for use in treatment of diseases or syndromes. These viruses do not result in a productive infection because they lack critical genes for viral replication, but they do carry DNA sequences that allow them to be packaged into infectious particles. Once in the host cell the viral DNA is released and integrates into the cell's genome. The advantage to this strategy is that the delivery of the DNA is very efficient. What is one possible problem of using a virus that can integrate into the human nuclear genome? Multiple Choice The virus carries genes that will interfere with host cell activities. The viral DNA sequences could still cause a disease. Since the viral DNA sequences no longer contain essential genes for viral replication the host cell may not be able to replicate either. The integration could disrupt an essential gene or genes.arrow_forwardWhat enzyme is responsible for the production of viral DNA from a retrovirus?arrow_forwardCoronaviruses have a positive-sense single stranded RNA genome. a.) What is the genome replication strategy of this category of viruses? b.) How do you think this feature affects the stability of the viral genome? (hint use figure below) Mutation rates in different types of viruses. Estimates obtained for viruses belonging to the major indicated groups are shown as a function of genome size. This reveals an effect of genetic material (RNA/DNA) and genome size on viral mutation rates.arrow_forward
- Name a nucleoside analog. Explain how that nucleoside analog works. Which viruses are effectively treated by that nucleoside analog?arrow_forwardSimian Virus 40 is carcinogenic in primates. 1). which molecule of the virus 2). what particular property of the molecule that enable the malignant transformation.arrow_forwardMatch each of the following replication classes of viruses with the one description that best describes it. This virus class is composed of segmented and non-segmented helical viruses that carry an RdRp within the virion into the cell. Example: Rabies virus These viruses are non- enveloped, icosahedral, have segmented genomes, and carry their own RNA-dependent RNA polymerase. The viral genome is copied following assembly. Example: Reovirus This is the only class of RNA viruses whose genome is replicated by cellular enzymes and not an RNA-dependent RNA polymerase. Cellular DNA polymerases replicate this virus's non- integrated genome, although transcription is not the initial event that takes place in the process. Example: Parvoviruses In this class of viruses, transcription occurs before genome replication because viral proteins are involved in replicating the genome. Example: Adenovirus This class of viruses forms circular DNA and creates pre- genomic RNA using host RNA polymerases.…arrow_forward
- A viral particle adsorbs onto a host cell membrane. It uncoats and releases its single-stranded nonsegmented nucleic acid into the cytoplasm where it is immed dependent RNA polymerase, into mRNA. It is then translated into viral structural proteins and enzymes. Which of the following virus families is most likely repre A) Herpesviridae B) Paramyxoviridae C) Parvoviridae D) Reovirius E) Retroviridaearrow_forwardHow do retroviruses use the enzyme reverse transcriptase?arrow_forwardModerna and Pfizer vaccines for COVID-19 use mRNA to the Spike protein combined with lipids. Which of the following is/are advantages of this type of vaccine compared to an inactivated virus vaccine? Select ALL correct answers. a) The vaccine is more stable for transport. b) The vaccine does not contain the virus so it cannot give you COVID-19. c) The vaccine can be rapidly produced in a slightly different form to protect from variants of SARS-CoV-2. d) The vaccine does not need a booster.arrow_forward
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