Essential Cell Biology (fifth Edition)
Essential Cell Biology (fifth Edition)
5th Edition
ISBN: 9780393680362
Author: ALBERTS, Bruce, Hopkin, Karen, Johnson -
Publisher: W. W. Norton & Company
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Chapter 18, Problem 4Q
Summary Introduction

To explain: The consequences of cell replicating with damaged DNA without repairing it.

Concept introduction: The DNA has several damages due to several mutagens (mutation causing agents), which causes mutations in the DNA. These damages are reversed during the process of replication by several repair mechanisms. But at times, these repair mechanisms failed either due to the loss of proteins involved in these repair mechanisms or failure to activate these mechanisms post-G1 phase during the G1/S check points.

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