Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 18, Problem 22RA
Describe the mechanisms that are believed to protect the gastric mucosa from self-digestion. What factors might be responsible for the development of a peptic ulcer in the stomach?
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 18 Solutions
Human Physiology
Ch. 18 - Prob. 1aCPCh. 18 - Describe the structure and function of the mucosa,...Ch. 18 - Prob. 2bCPCh. 18 - Describe the structure and function of the lower...Ch. 18 - Prob. 3bCPCh. 18 - Prob. 4aCPCh. 18 - Explain how peptic ulcers are produced and why...Ch. 18 - Explain how gastrin and vagus nerve stimulation...Ch. 18 - Describe the adaptations of the small intestine...Ch. 18 - Prob. 6CP
Ch. 18 - Prob. 7CPCh. 18 - Prob. 8aCPCh. 18 - Prob. 8bCPCh. 18 - Prob. 9CPCh. 18 - Prob. 10aCPCh. 18 - Prob. 10bCPCh. 18 - Prob. 10cCPCh. 18 - Prob. 11aCPCh. 18 - Prob. 11bCPCh. 18 - Prob. 12CPCh. 18 - Prob. 13aCPCh. 18 - Describe the mechanisms involved in the intestinal...Ch. 18 - Prob. 14CPCh. 18 - Prob. 15CPCh. 18 - Prob. 16aCPCh. 18 - List each enzyme involved in protein digestion....Ch. 18 - Describe how bile aids both the digestion and...Ch. 18 - Trace the pathway and fate of a molecule of...Ch. 18 - Prob. 17cCPCh. 18 - Which of these statements about intrinsic factor...Ch. 18 - Prob. 2RACh. 18 - Which of these statements about gastric secretion...Ch. 18 - Prob. 4RACh. 18 - Which of these statements about trypsin is...Ch. 18 - Prob. 6RACh. 18 - Prob. 7RACh. 18 - The first organ to receive the blood-borne...Ch. 18 - Prob. 9RACh. 18 - Prob. 10RACh. 18 - Prob. 11RACh. 18 - Which of these statements about vitamin is...Ch. 18 - Which of these statements about starch digestion...Ch. 18 - Prob. 14RACh. 18 - Which of these statements about contraction of...Ch. 18 - Prob. 16RACh. 18 - Prob. 17RACh. 18 - Which of the following statements about the liver...Ch. 18 - Prob. 19RACh. 18 - Prob. 20RACh. 18 - Prob. 21RACh. 18 - Describe the mechanisms that are believed to...Ch. 18 - Prob. 23RACh. 18 - Explain how jaundice is produced when (a) the...Ch. 18 - Prob. 25RACh. 18 - Distinguish between chylomicrons, very-low-density...Ch. 18 - Prob. 27RACh. 18 - Trace the course of blood flow through the liver...Ch. 18 - Prob. 29RACh. 18 - Describe the reflexes controlling the stomach,...Ch. 18 - Prob. 31RACh. 18 - Prob. 32RACh. 18 - Prob. 33RACh. 18 - Prob. 34RACh. 18 - Prob. 35RACh. 18 - Prob. 36RACh. 18 - Prob. 37RACh. 18 - Prob. 38RACh. 18 - Prob. 39RACh. 18 - Prob. 40RACh. 18 - Refer to figure 18. I 4 to answer the following...Ch. 18 - Prob. 42RACh. 18 - Prob. 43RA
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