Genetics: From Genes To Genomes (6th International Edition)
6th Edition
ISBN: 9781260041217
Author: Leland Hartwell Dr., ? Michael L. Goldberg Professor Dr., ? Janice Fischer, ? Leroy Hood Dr.
Publisher: Mcgraw-Hill
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Textbook Question
Chapter 18, Problem 15P
| a. | Diagram a knockin construct that could have been used to create the mouse model for achondroplasia shown in Fig. 18.13. |
| b. | Explain how CRISPR/Cas9 could have been used to produce a mouse model for this condition. |
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Chapter 18 Solutions
Genetics: From Genes To Genomes (6th International Edition)
Ch. 18 - Match each of the terms in the left column to the...Ch. 18 - Mice are usually gray, but a mouse geneticist has...Ch. 18 - Sometimes, genes transferred into the mouse genome...Ch. 18 - In mice, a group of so-called Hox genes encode...Ch. 18 - The fly eyes shown in Fig. 18.7 are malformed...Ch. 18 - This problem concerns a technique called enhancer...Ch. 18 - Fish and other organisms that live in the Arctic...Ch. 18 - a. Describe two ways you could potentially make a...Ch. 18 - Figure 18.6 shows a picture of Glofish ,...Ch. 18 - Some people are concerned about the possible...
Ch. 18 - The goal of the Knockout Mouse Project is to...Ch. 18 - Prob. 12PCh. 18 - Prob. 13PCh. 18 - a. Which genome manipulation technique would you...Ch. 18 - a. Diagram a knockin construct that could have...Ch. 18 - Prob. 16PCh. 18 - Prob. 17PCh. 18 - The transcription factor Pax6 is required...Ch. 18 - Mouse models for human genetic diseases are...Ch. 18 - One way to determine where inside a cell a protein...Ch. 18 - In Problem 5 in Chapter 17, you saw that a SNP...Ch. 18 - Scientists now routinely use CRISPR/Cas9 to make...Ch. 18 - Geneticists are currently considering using...Ch. 18 - a. Figures 18.9 and 18.12 demonstrated methods to...Ch. 18 - Nonhomologous end-joining NHEJ of a double-strand...Ch. 18 - One problem that researchers sometimes encounter...Ch. 18 - Researchers at the University of California at San...Ch. 18 - Prob. 28PCh. 18 - F. Port and S. Bullock at the University of...Ch. 18 - On Fig 18.14, locate the PAM site and identify the...Ch. 18 - Prob. 31PCh. 18 - Prob. 32PCh. 18 - Recall that Leber congenital amaurosis LCA, a form...Ch. 18 - One potential strategy for gene therapy to correct...Ch. 18 - Recently, scientists have used a mouse model for...
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- Identify the indicated tissue? (stem x.s.) parenchyma collenchyma sclerenchyma ○ xylem ○ phloem none of thesearrow_forwardWhere did this structure originate from? (Salix branch root) epidermis cortex endodermis pericycle vascular cylinderarrow_forwardIdentify the indicated tissue. (Tilia stem x.s.) parenchyma collenchyma sclerenchyma xylem phloem none of thesearrow_forward
- Identify the indicated structure. (Cucurbita stem l.s.) pit lenticel stomate tendril none of thesearrow_forwardIdentify the specific cell? (Zebrina leaf peel) vessel element sieve element companion cell tracheid guard cell subsidiary cell none of thesearrow_forwardWhat type of cells flank the opening on either side? (leaf x.s.) vessel elements sieve elements companion cells tracheids guard cells none of thesearrow_forward
- What specific cell is indicated. (Cucurbita stem I.s.) vessel element sieve element O companion cell tracheid guard cell none of thesearrow_forwardWhat specific cell is indicated? (Aristolochia stem x.s.) vessel element sieve element ○ companion cell O O O O O tracheid O guard cell none of thesearrow_forwardIdentify the tissue. parenchyma collenchyma sclerenchyma ○ xylem O phloem O none of thesearrow_forward
- Please answer q3arrow_forwardRespond to the following in a minimum of 175 words: How might CRISPR-Cas 9 be used in research or, eventually, therapeutically in patients? What are some potential ethical issues associated with using this technology? Do the advantages of using this technology outweigh the disadvantages (or vice versa)? Explain your position.arrow_forwardYou are studying the effect of directional selection on body height in three populations (graphs a, b, and c below). (a) What is the selection differential? Show your calculation. (2 pts) (b) Which population has the highest narrow sense heritability for height? Explain your answer. (2 pts) (c) If you examined the offspring in the next generation in each population, which population would have the highest mean height? Why? (2 pts) (a) Midoffspring height (average height of offspring) Short Short Short Short (c) Short (b) Short Tall Short Tall Short Short Tall Midparent height (average height of Mean of population = 65 inches Mean of breading parents = 70 inches Mean of population = 65 inches Mean of breading parents = 70 inches Mean of population = 65 inches Mean of breading parents = 70 inchesarrow_forward
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