Chapter 17.5, Problem 13LO

Summary Introduction

To describe: How lipid-soluble hormones reach their target cell receptors and the type of cellular change they initiate.

Concept introduction: Lipid-soluble hormones such as steroids and calcitriol are small, non-polar molecules known as lipophilic. They are relatively small. Therefore, they can easily enter in the plasma membrane. After diffusion in the plasma membrane, they can bind to their receptors that are located in the nucleus or cytoplasm.