Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 17, Problem 17PDQ
DNA supercoiling, which occurs when coiling tension is generated ahead of the replication fork, is relieved by DNA gyrase. Supercoiling may also be involved in transcription regulation. Researchers discovered that enhancers operating over a long distance (2500 bp) are dependent on DNA supercoiling, while enhancers operating over shorter distances (110 bp) are not so dependent [Liu et al. (2001). Proc. Natl. Acad. Sci. USA 98:14,883–14,888]. Using a diagram, suggest a way in which supercoiling may positively influence enhancer activity over long distances.
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Chapter 17 Solutions
Concepts of Genetics (11th Edition)
Ch. 17 - Cancer cells often have abnormal patterns of...Ch. 17 - The hormone estrogen converts the estrogen...Ch. 17 - Prob. 3NSTCh. 17 - Prob. 1CSCh. 17 - A man in his early 30s suddenly developed weakness...Ch. 17 - Prob. 3CSCh. 17 - Prob. 1PDQCh. 17 - Prob. 2PDQCh. 17 - Prob. 3PDQCh. 17 - Provide a definition of chromatin remodeling, and...
Ch. 17 - Describe the organization of the interphase...Ch. 17 - A number of experiments have demonstrated that...Ch. 17 - Prob. 7PDQCh. 17 - Present an overview of the manner in which...Ch. 17 - Distinguish between the cis-acting regulatory...Ch. 17 - Describe the manner in which activators and...Ch. 17 - Compare the control of gene regulation in...Ch. 17 - Many promoter regions contain CAAT boxes...Ch. 17 - Prob. 13PDQCh. 17 - Present an overview of RNA-induced gene silencing...Ch. 17 - Prob. 15PDQCh. 17 - Prob. 16PDQCh. 17 - DNA supercoiling, which occurs when coiling...Ch. 17 - Prob. 18PDQCh. 17 - Prob. 19PDQCh. 17 - Prob. 20ESPCh. 17 - Prob. 21ESPCh. 17 - Because the degree of DNA methylation appears to...Ch. 17 - Prob. 23ESPCh. 17 - Prob. 24ESPCh. 17 - Prob. 25ESPCh. 17 - Prob. 26ESPCh. 17 - Prob. 27ESPCh. 17 - Prob. 28ESPCh. 17 - During an examination of the genomic sequences...Ch. 17 - Transcription factors play key roles in the...
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