Chapter 17, Problem 14PDQ

Summary Introduction

To represent:

An overview RNA-induced gene silencing which is achieved through RNA interference (RNAi). How does the silencing process begin and what are the major components involved in it?

Introduction:

The process of regulation of gene expression to prevent the expression of a particular gene is referred to as gene silencing. It could occur either during the translation or transcription process. This modification in gene expression could also be carried out by small RNA molecules. They act in the nucleus in order to alter the chromatin structure and to bring about the repression of the transcription process. It also represses translation and triggers mRNAs degradation. This phenomenon together is known as RNA induced gene silencing.