Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Question
Chapter 17, Problem 11P
Interpretation Introduction
nterpretation:
The most probable mechanism for the inhibition of pyruvate kinase by the action of glucagon on the liver cells.
Concept introduction:
The glucagon consists of 29 amino acids and is secreted from the alpha cells of the pancreas. The precursor molecule for this hormone is the proglucagon, which is also the precursor of the GLP-1 and the GLP-2. The sequence of the glucagon is highly conserved among all the vertebrates.
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10. Which one of the
following compounds is
the major organic product
of the series of reactions
shown here?
Ph
A
OH
Ph
B
CO₂Et
Br
-H
Ν ΚΑ
CO₂Et
1. NaOEt
1. NaOH, H₂O
2. H3O+
2. PhCH2CH2Br
3. heat
NH2
Ph
OH
NH2
0
OH
Ph
OH
NH2
Ph
D
NH2
E
OH
1. What is the isoelectric point of glutamic acid?
(Glutamic acid has pKa1 2.10, pKa2 4.07, pKaз 9.47)
A) pH 2.1
D) pH 6.8
B) pH 3.1
C) pH 4.1
E) pH 9.5
HO
NH2
Glutamic acid
(shown without charges)
OH
Br
Mg, ether
1. HCHO
(formaldehyde)
2. H+, H₂O
PCC
1. NH3, HCN
?
(pyridinium chlorochromate)
2. H2O, HCI
11. Which one of the following compounds is the major organic product of the
series of reactions shown above?
Ph.
Ph.
OH
NH2₂
A
Ph.
Ή
NH2
B
OH
Ph
Η
Ph
OH
NH2
NH2₂
NH₂
C
D
E
Chapter 17 Solutions
Biochemistry: Concepts and Connections (2nd Edition)
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