Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 16, Problem 8MCQ
Summary Introduction
Introduction:
An autoantibody is a type of protein or antibody produced by the immune system that acts against one or more of the individual's own proteins. Most of the autoimmune diseases are caused by such auto-antibodies.
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CHAPTER 20
The Lymphatic System and Immunity
Matching
SECTION 3 Revie w
Match each lettered term with the most closely related description.
a. opsonization
1
b. helper T cells
Two parallel pairs of polypeptide chains
Found on helper T cells
C. antibody
d. class II MHC
3
Active and passive
4 Transfer of antibodies
e. costimulation
Attacked by HIV
f. IgM
6 Enhances phagocytosis
g. class I MHC
h. IgG
7 MHC proteins present in the plasma
membranes of all nucleated cells
i. passive immunity
j. anaphylaxis
8
Differentiate into memory and plasma cells
9
MHC proteins present in the plasma
membranes of all APCS and lymphocytes
9
k. CD4 markers
10
I. acquired immunity
10 Antibodies used to determine blood type
11
m. B lymphocytes
11 Secondary binding process required for T cell activation
12
12 Accounts for 80 percent of all immunoglobulins
13
13 Circulating allergen stimulates mast cells throughout body
Match each lettered term with the
Which of the following statements are true for antigen presentation.
a.
Antigen presentation means that other cells attach the pathogen first and present it to T cells.
b.
Antigen-presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor to B cells
c.
Antigen presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor on their surface.
d.
Antigen-presenting cells are phagocytic cells
e.
Antigen presentation is required for T cell activation
f.
Cytokines released by macrophages are required for T cell activation
g.
T cell receptors recognize the MHC receptors in complex with antigen fragments displayed by antigen-presenting cells.
h.
Phagocytic cells are involved in innate immunity. Therefore they have no role in T-cell activation
Which of the following is TRUE about B cells?
A. are lymphocytes
B. become mature in the thymus
C. are responsible for cell-mediated immunity
D. are produced in the adult spleen
Chapter 16 Solutions
Microbiology: A Systems Approach
Ch. 16.1 - Define immunopathology, and describe the two major...Ch. 16.1 - Prob. 2AYPCh. 16.2 - Prob. 3AYPCh. 16.2 - Outline the steps of a type I allergic response,...Ch. 16.2 - Identify three conditions caused by IgE-mediated...Ch. 16.2 - Prob. 6AYPCh. 16.2 - Prob. 7AYPCh. 16.2 - Prob. 8AYPCh. 16.3 - List the three immune components causing cell...Ch. 16.3 - Prob. 10AYP
Ch. 16.3 - Prob. 11AYPCh. 16.4 - Prob. 12AYPCh. 16.4 - Prob. 13AYPCh. 16.5 - Prob. 14AYPCh. 16.5 - List four classes of grafts, and explain how host...Ch. 16.6 - Prob. 16AYPCh. 16.6 - Prob. 17AYPCh. 16.7 - Prob. 18AYPCh. 16.7 - Prob. 19AYPCh. 16.7 - Prob. 20AYPCh. 16 - Prob. 1MCQCh. 16 - Prob. 2MCQCh. 16 - The contact with allergen that results in symptoms...Ch. 16 - Prob. 4MCQCh. 16 - Prob. 5MCQCh. 16 - Prob. 6MCQCh. 16 - Prob. 7MCQCh. 16 - Prob. 8MCQCh. 16 - Prob. 9MCQCh. 16 - Prob. 10MCQCh. 16 - Prob. 11TFCh. 16 - Prob. 12TFCh. 16 - Prob. 13TFCh. 16 - Prob. 14TFCh. 16 - Prob. 15TFCh. 16 - Prob. 1CTQCh. 16 - Summarize the roles of the microbiome and genetics...Ch. 16 - Prob. 3CTQCh. 16 - Prob. 4CTQCh. 16 - Prob. 5CTQCh. 16 - From chapter 15. figure 15.1. How would a persons...Ch. 16 - Prob. 2VCCh. 16 - Prob. 1CM
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- Which of the following is not a function of antibodies? Select one: a. They neutralize pathogens by masking the pathogen surface. b. They act as molecular adaptors that bridge together pathogen and phagocyte surfaces. c. They exert toxic effects directly. d. They act as opsonins that mediate phagocytosis. e. They activate complement fixation.arrow_forwardThe following events occur in humoral immunity, leading to an activated B cell in a T dependent manner. Of the steps listed below, which would be step number 5 in the process. Hint: only include these steps in the numbering...order the steps and select which one is #5 A. secretion of cytokines by Th B. Receptor mediated endocytosis C. B cell receptors recognize and bind to an antigen D. Recognition by Th E. Digestion and processing of the antigen by the B cell F. Display of the antigen along with MHC proteinsarrow_forwardAll of the following are functions of antibodies except a. neutralization of pathogen. b. destruction of antigen. c. agglutination of antigen. d. opsonization.arrow_forward
- Which of the following is a critical feature ofimmediate hypersensitivity?a. inflammationb. cytotoxic T cellsc. recruitment of immune cellsd. histamine releasearrow_forwardAntibodies can have multiple mechanisms of action. The main mechanism is "flagging" a foreign body for phagocytosis and degradation. Another mechanism is... Select one: a. Binding of the Fc domain to T cells for cooperative antigen recognition and destruction. b. Altering the local pH by the formation of carbamate upon reaction with CO2 to denature protein antigens. c. Binding of the variable region to multiple different/distinct sites on the antigen. d. None of these. e. Binding of the antigen in regions essential for its function.arrow_forwardWhich of the following is false about HLA class I molecules? A. They are encoded by multiple and highly polymorphic genes. B. They consist of alpha and beta chains. C. They possess beta-2 microglobulin. D. They present foreign antigens to cytotoxic T cells. E. none of the abovearrow_forward
- During allergic sensitization, which of the following statements are FALSE? A. Allergen exposure coincides with unrelated damage B. Dendritic cells induce IL-6 production by TH2 CD4+ T cells during TH2 cell differentiation C. Damage induces the production of alarmins like IL-25 D. TFH cells bind to B cells via CD40L to CD40 and produce IL-4arrow_forwardIndicate to which branch(es) of the immune system the following statements apply, using H for the humoral branch and CM for the cell-mediated branch. Some statements may apply to both branches (B). a. Involves B cells b. Involves T cells c. Responds to extracellular bacterial infection d. Involves secreted antibody e. Kills virus-infected self cellsarrow_forwardAll of the following are true in reference to T- cell priming except a. it occurs in primary lymphoid organs b. it transforms naive T cells into differentiated effector T cells c. it is the first stage of a primary adaptive immune response d. it requires interaction between naive T cells and antigen-presenting cells e. it takes place in many locations including, but not limited to, lymph nodes, Peyer's patches, and the tonsils.arrow_forward
- Explain why each choice (a-d) is correct or incorrect. Which statement is true about T cells? a. They usually directly recognize antigens, which then activates a subpopulation of killer cells b. Their proliferation is enhanced by interleukins 1 and 2. c. Once activated, they cannot secrete cytokines. d. They will develop into cytotoxic T cells if antigen is complexed with class II MHC proteins.arrow_forwardExplain the typical immunophenotypic features of peripheral B cells in: (i) X-linked Agammaglobulinaemia (ii) CD40L (CD154) deficiency (iii) B-Chronic Lymphocytic Leukaemia. wwarrow_forwardWhich of the following pairs is mismatched? a. T-cell activation: cell division and differentiation b. effector B cell: plasma cell c. plasma cell: antibody secretion d. helper T cell: kills pathogen-infected cells e. helper T cell: facilitates the differentiation of B cells.arrow_forward
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