Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 16.7, Problem 18AYP
Summary Introduction
To differentiate:
Between primary and secondary immunodeficiencies, explaining how each develops.
Concept introduction:
Immunodeficiency is a state in which the ability of the immune system to fight against the infectious disease and cancer is entirely absent or is compromised. Most of the cases of immunodeficiency are acquired due to extrinsic factors and some of them are inherited.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 16 Solutions
Microbiology: A Systems Approach
Ch. 16.1 - Define immunopathology, and describe the two major...Ch. 16.1 - Prob. 2AYPCh. 16.2 - Prob. 3AYPCh. 16.2 - Outline the steps of a type I allergic response,...Ch. 16.2 - Identify three conditions caused by IgE-mediated...Ch. 16.2 - Prob. 6AYPCh. 16.2 - Prob. 7AYPCh. 16.2 - Prob. 8AYPCh. 16.3 - List the three immune components causing cell...Ch. 16.3 - Prob. 10AYP
Ch. 16.3 - Prob. 11AYPCh. 16.4 - Prob. 12AYPCh. 16.4 - Prob. 13AYPCh. 16.5 - Prob. 14AYPCh. 16.5 - List four classes of grafts, and explain how host...Ch. 16.6 - Prob. 16AYPCh. 16.6 - Prob. 17AYPCh. 16.7 - Prob. 18AYPCh. 16.7 - Prob. 19AYPCh. 16.7 - Prob. 20AYPCh. 16 - Prob. 1MCQCh. 16 - Prob. 2MCQCh. 16 - The contact with allergen that results in symptoms...Ch. 16 - Prob. 4MCQCh. 16 - Prob. 5MCQCh. 16 - Prob. 6MCQCh. 16 - Prob. 7MCQCh. 16 - Prob. 8MCQCh. 16 - Prob. 9MCQCh. 16 - Prob. 10MCQCh. 16 - Prob. 11TFCh. 16 - Prob. 12TFCh. 16 - Prob. 13TFCh. 16 - Prob. 14TFCh. 16 - Prob. 15TFCh. 16 - Prob. 1CTQCh. 16 - Summarize the roles of the microbiome and genetics...Ch. 16 - Prob. 3CTQCh. 16 - Prob. 4CTQCh. 16 - Prob. 5CTQCh. 16 - From chapter 15. figure 15.1. How would a persons...Ch. 16 - Prob. 2VCCh. 16 - Prob. 1CM
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