Microbiology: A Systems Approach
Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 16, Problem 12TF
Summary Introduction

Introduction:

Type IV reactions are caused when T cells respond against antigens displayed in the cells of the body itself or transplanted from another individual. Type IV immune dysfunction is also known as delayed hypersensitivity because the symptoms arise after several days following the second contact with an antigen.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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