EBK HUMAN PHYSIOLOGY
15th Edition
ISBN: 9781260163049
Author: Fox
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 16, Problem 45RA
Summary Introduction
To review:
The percentage of oxygen unloading with respect to the case given.
Introduction:
The transportation of oxygen by the red blood cells (RBCs) involves the loading and unloading reactions. The bonding of oxygen with the hemoglobin in the lungs is termed as the loading reaction. The unloading of oxygen in the tissues from the hemoglobin is termed as the unloading reaction.
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A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation?
The cell membranes are more resistant than normal.
An isotonic solution had been added instead of water.
A solution of 0.1 M NaCl had been added instead of water.
Not enough water had been added to the red blood cell pellet.
The man had sickle-cell anaemia.
A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation?
The cell membranes are more resistant than normal.
An isotonic solution had been added instead of water.
A solution of 0.1 M NaCl had been added instead of water.
Not enough water had been added to the red blood cell pellet.
The man had sickle-cell anaemia.
With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin
Chapter 16 Solutions
EBK HUMAN PHYSIOLOGY
Ch. 16 - Describe the structures involved in gas exchange...Ch. 16 - Prob. 1bCPCh. 16 - Describe how each lung is compartmentalized by the...Ch. 16 - Describe the changes in the intrapulmonary and...Ch. 16 - Explain how the compliance and elasticity of the...Ch. 16 - Describe pulmonary surfactant and discuss its...Ch. 16 - Describe the actions of the diaphragm and external...Ch. 16 - Explain how forced inspiration and forced...Ch. 16 - Define the terms tidal volume and vital capacity....Ch. 16 - How are the vital capacity and the forced...
Ch. 16 - Explain how the of air is calculated and how this...Ch. 16 - Explain how blood measurements are taken, and...Ch. 16 - Explain how the arterial and the oxygen content...Ch. 16 - Describe the ventilation/perfusion ratios of the...Ch. 16 - Explain how decompression sickness is produced in...Ch. 16 - Describe the roles of centers in the brain stem...Ch. 16 - Describe the effects of voluntary hyperventilation...Ch. 16 - Using a flowchart to show a negative feedback...Ch. 16 - Prob. 10bCPCh. 16 - Prob. 10cCPCh. 16 - Use a graph to illustrate the effects of Po2 on...Ch. 16 - Draw an oxyhemoglobin dissociation curve and label...Ch. 16 - Prob. 12aCPCh. 16 - Prob. 12bCPCh. 16 - List the ways in which carbon dioxide is carried...Ch. 16 - Where in the body does the chloride shift occur?...Ch. 16 - Where in the body does a reverse chloride shift...Ch. 16 - Using equations, show how carbonic acid and...Ch. 16 - Prob. 15aCPCh. 16 - Prob. 15bCPCh. 16 - Prob. 15cCPCh. 16 - Prob. 15dCPCh. 16 - Explain why a person with ketoacidosis...Ch. 16 - Prob. 16aCPCh. 16 - Explain why endurance-trained athletes have a...Ch. 16 - Prob. 17CPCh. 16 - Prob. 1RACh. 16 - Prob. 2RACh. 16 - The maximum amount of air that can be expired...Ch. 16 - Prob. 4RACh. 16 - Prob. 5RACh. 16 - Which of these would be most affected by a...Ch. 16 - Prob. 7RACh. 16 - Prob. 8RACh. 16 - The affinity of hemoglobin for oxygen is decreased...Ch. 16 - Prob. 10RACh. 16 - The bicarbonate concentration or the blood would...Ch. 16 - Prob. 12RACh. 16 - Prob. 13RACh. 16 - Which of these occur(s) during hypoxemia?...Ch. 16 - During exercise, which of these statements is...Ch. 16 - All of the following can bond with hemoglobin...Ch. 16 - Prob. 17RACh. 16 - The hypoxic ventilatory response occurs when low...Ch. 16 - Using a flow diagram to show cause and effect,...Ch. 16 - Radiographic (x-ray) pictures show that the rib...Ch. 16 - Explain, using a flowchart, how a rise in blood ...Ch. 16 - Explain why a person with ketoacidosis may...Ch. 16 - Prob. 23RACh. 16 - Explain how measurements of blood Pco2,...Ch. 16 - Describe the changes in ventilation that occur...Ch. 16 - Prob. 26RACh. 16 - Describe how ventilation changes when a person...Ch. 16 - Explain the physiological changes in the blood's...Ch. 16 - Compare asthma and emphysema in terms of their...Ch. 16 - Explain the mechanisms involved in quiet...Ch. 16 - Describe the formation, composition, and function...Ch. 16 - Prob. 32RACh. 16 - The nature of the sounds produced by percussion...Ch. 16 - Explain why the fast breath of a healthy neonate...Ch. 16 - Prob. 35RACh. 16 - Carbon monoxide poisoning from smoke inhalation...Ch. 16 - Prob. 37RACh. 16 - Explain how a subatmospheric intrapleural pressure...Ch. 16 - Prob. 39RACh. 16 - You cannot affect the oxygen delivery to your...Ch. 16 - Refer to figure 16.19 and calculate the Po2 of the...Ch. 16 - Refer to figure 16.19 and calculate the of the...Ch. 16 - Refer to figure 16.19 and calculate the Po2 of the...Ch. 16 - Use figure 16.34 to answer the following...Ch. 16 - Prob. 45RACh. 16 - Use figure 16.34 to answer the following...Ch. 16 - Prob. 47RA
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- With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobinarrow_forwardWhich ONE of the following is FALSE regarding haemoglobin? It has two alpha subunits and two beta subunits. The subunits are joined by disulphide bonds. Each subunit covalently binds a haem group. Conformational change in one subunit can be transmitted to another. There are many variant ("mutant") forms of haemoglobin that are not harmful.arrow_forwardWhich ONE of the following is FALSE regarding haemoglobin? It has two alpha subunits and two beta subunits. The subunits are joined by disulphide bonds. Each subunit covalently binds a haem group. Conformational change in one subunit can be transmitted to another. There are many variant ("mutant") forms of haemoglobin that are not harmful.arrow_forward
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