EBK HUMAN PHYSIOLOGY
15th Edition
ISBN: 9781260163049
Author: Fox
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 16, Problem 16RA
All of the following can bond with hemoglobin except
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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
There is currently a H5N1 cattle outbreak in North America.
According to the CDC on Feb 26*: "A multistate outbreak of HPAI A(H5N1) bird flu in dairy cows was first reported on March 25, 2024. This is the first time that these bird flu viruses had been found in cows. In the United States, since 2022, USDA has reported HPAI A(H5N1) virus detections in more than 200 mammals."
List and describe two mechanisms that could lead to this H5N1 influenza strain evolving to spread in human:
Mechanisms 1:
Mechanisms 2:
For the mutations to results in a human epidered they would need to change how the virus interacts with the human host. In the case of mutations that may promote an epidemic, provide an example for:
a protein that might incur a mutation:
how the mutation would change interactions with cells in the respiratory tract (name the receptor on human cells)
List two phenotypic consequence from this mutation that would increase human risk
Chapter 16 Solutions
EBK HUMAN PHYSIOLOGY
Ch. 16 - Describe the structures involved in gas exchange...Ch. 16 - Prob. 1bCPCh. 16 - Describe how each lung is compartmentalized by the...Ch. 16 - Describe the changes in the intrapulmonary and...Ch. 16 - Explain how the compliance and elasticity of the...Ch. 16 - Describe pulmonary surfactant and discuss its...Ch. 16 - Describe the actions of the diaphragm and external...Ch. 16 - Explain how forced inspiration and forced...Ch. 16 - Define the terms tidal volume and vital capacity....Ch. 16 - How are the vital capacity and the forced...
Ch. 16 - Explain how the of air is calculated and how this...Ch. 16 - Explain how blood measurements are taken, and...Ch. 16 - Explain how the arterial and the oxygen content...Ch. 16 - Describe the ventilation/perfusion ratios of the...Ch. 16 - Explain how decompression sickness is produced in...Ch. 16 - Describe the roles of centers in the brain stem...Ch. 16 - Describe the effects of voluntary hyperventilation...Ch. 16 - Using a flowchart to show a negative feedback...Ch. 16 - Prob. 10bCPCh. 16 - Prob. 10cCPCh. 16 - Use a graph to illustrate the effects of Po2 on...Ch. 16 - Draw an oxyhemoglobin dissociation curve and label...Ch. 16 - Prob. 12aCPCh. 16 - Prob. 12bCPCh. 16 - List the ways in which carbon dioxide is carried...Ch. 16 - Where in the body does the chloride shift occur?...Ch. 16 - Where in the body does a reverse chloride shift...Ch. 16 - Using equations, show how carbonic acid and...Ch. 16 - Prob. 15aCPCh. 16 - Prob. 15bCPCh. 16 - Prob. 15cCPCh. 16 - Prob. 15dCPCh. 16 - Explain why a person with ketoacidosis...Ch. 16 - Prob. 16aCPCh. 16 - Explain why endurance-trained athletes have a...Ch. 16 - Prob. 17CPCh. 16 - Prob. 1RACh. 16 - Prob. 2RACh. 16 - The maximum amount of air that can be expired...Ch. 16 - Prob. 4RACh. 16 - Prob. 5RACh. 16 - Which of these would be most affected by a...Ch. 16 - Prob. 7RACh. 16 - Prob. 8RACh. 16 - The affinity of hemoglobin for oxygen is decreased...Ch. 16 - Prob. 10RACh. 16 - The bicarbonate concentration or the blood would...Ch. 16 - Prob. 12RACh. 16 - Prob. 13RACh. 16 - Which of these occur(s) during hypoxemia?...Ch. 16 - During exercise, which of these statements is...Ch. 16 - All of the following can bond with hemoglobin...Ch. 16 - Prob. 17RACh. 16 - The hypoxic ventilatory response occurs when low...Ch. 16 - Using a flow diagram to show cause and effect,...Ch. 16 - Radiographic (x-ray) pictures show that the rib...Ch. 16 - Explain, using a flowchart, how a rise in blood ...Ch. 16 - Explain why a person with ketoacidosis may...Ch. 16 - Prob. 23RACh. 16 - Explain how measurements of blood Pco2,...Ch. 16 - Describe the changes in ventilation that occur...Ch. 16 - Prob. 26RACh. 16 - Describe how ventilation changes when a person...Ch. 16 - Explain the physiological changes in the blood's...Ch. 16 - Compare asthma and emphysema in terms of their...Ch. 16 - Explain the mechanisms involved in quiet...Ch. 16 - Describe the formation, composition, and function...Ch. 16 - Prob. 32RACh. 16 - The nature of the sounds produced by percussion...Ch. 16 - Explain why the fast breath of a healthy neonate...Ch. 16 - Prob. 35RACh. 16 - Carbon monoxide poisoning from smoke inhalation...Ch. 16 - Prob. 37RACh. 16 - Explain how a subatmospheric intrapleural pressure...Ch. 16 - Prob. 39RACh. 16 - You cannot affect the oxygen delivery to your...Ch. 16 - Refer to figure 16.19 and calculate the Po2 of the...Ch. 16 - Refer to figure 16.19 and calculate the of the...Ch. 16 - Refer to figure 16.19 and calculate the Po2 of the...Ch. 16 - Use figure 16.34 to answer the following...Ch. 16 - Prob. 45RACh. 16 - Use figure 16.34 to answer the following...Ch. 16 - Prob. 47RA
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