EP MICROBIOLOGY:W/DISEASES BY..-MOD.ACC
5th Edition
ISBN: 9780134607894
Author: BAUMAN
Publisher: PEARSON CO
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Chapter 16, Problem 2MC
Summary Introduction
Introduction:
Major histocompatibility complex (MHC) gene is located on chromosome 6 and it code for MHC protein. MHC proteins are classified into two (MHC I and MHC II), these cell surface proteins recognize antigens and present them to immune cells.
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In regard to antigen presentation, MHC class I molecules usually present peptides derived from _____, whereas MHC class II molecules usually present peptides derived from _____.
a. intracellular cytosolic sources; vesicular system
b. phagolysosome; proteasomes
c. MIIC; self proteins
d. CLIP; HLA-DM
e. endocytic vesicles; endoplasmic reticulum.
MHCII molecules will bind __________ and locate to the cell surface.a. T-independent type antigensb. endogenous antigen c. autoantigens d. exogenous antigen
The two major types of phagocytic cells are_________ and_________.
Select one:
a. neutrophils; monocytes
b. monocytes; macrophages
c. eosinophils; T cells
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e. neutrophils; macrophages
Chapter 16 Solutions
EP MICROBIOLOGY:W/DISEASES BY..-MOD.ACC
Ch. 16 - Why are the activities of B and T cells called...Ch. 16 - Why are exogenous epitopes processed in vesicles...Ch. 16 - Why did scientists give the name perforin to a...Ch. 16 - Plasma cells are vital for protection against...Ch. 16 - Microsporidiosis Darius is sick, which is not...Ch. 16 - Why is passive immunity effective more quickly...Ch. 16 - Prob. 1MCCh. 16 - Prob. 2MCCh. 16 - Rejection of a foreign skin graft is an example of...Ch. 16 - An autoantigen is ________________. a. an antigen...
Ch. 16 - Among the key molecules that control cell-mediated...Ch. 16 - Which of the following lymphocytes predominates in...Ch. 16 - Prob. 7MCCh. 16 - Which cells express MHC class I molecules in a...Ch. 16 - In which of the following sites in the body can B...Ch. 16 - Tc cells recognize epitopes only when the latter...Ch. 16 - Prob. 1MTFCh. 16 - Prob. 2MTFCh. 16 - Prob. 3MTFCh. 16 - Prob. 4MTFCh. 16 - Prob. 5MTFCh. 16 - Match each cell in the left column with its...Ch. 16 - Match each type of immunity in the left column...Ch. 16 - Label the parts of the immunoglobulin below.Ch. 16 - The nearby image is a transmission electron...Ch. 16 - When is antigen processing an essential...Ch. 16 - Why does the body have both antibody and...Ch. 16 - Why is it advantageous for the lymphatic system to...Ch. 16 - Contrast innate defenses with adaptive immunity.Ch. 16 - How does requiring the immune system to process...Ch. 16 - Scientists can develop genetically deficient...Ch. 16 - Human immunodeficiency virus (HIV) preferentially...Ch. 16 - What would happen to a person who failed to make...Ch. 16 - Prob. 7CTCh. 16 - Some materials, such as metal bone pins and...Ch. 16 - Prob. 9CTCh. 16 - The cross-sectional area of the afferent lymphatic...Ch. 16 - Two students are studying for an exam on the bodys...Ch. 16 - In general, what sorts of pathogens might be able...Ch. 16 - What sorts of pathogens could successfully attack...Ch. 16 - As part of the treatment for some cancers,...Ch. 16 - Prob. 1CM
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Similar questions
- MHC class I molecules present peptide antigens derived from a(n) _______ compartment, whereas MHC class II molecules present peptide antigens derived from a(n) _______ compartment: a. extracellular; intracellular b. intracellular; extracellular c. opsonization; neutralization d. neutralization; opsonization e. none of the above.arrow_forward________ are released by helper T cells to mobilize immune cells and macrophages and attract other leukocytes into the area. A. Interleukin 2 proteins B. Lymphokines C. Interleukin 1 proteins D. Monokines Explain correct answer.arrow_forwardWhen an immature dendritic cell becomes an activated dendritic cell, all of the following changes occur except _____. a. confinement to T-cell regions of lymph node cortex b. development of elaborate finger-like processes c. upregulated expression of MHC class II at the cell surface d. loss of antigen-processing functions e. expression of Toll-like receptor TLR9.arrow_forward
- Why HIV doesn’t naturally induce a strong CD8+ T cell response? (Select all that apply if more than one option is correct.) a. The virus is not recognized by BCRs b. HIV antigens cannot be presented on MHC II c. HIV antigens cannot be presented on MHC I d. HIV does not readily infect non-T cells e. HIV cannot interact with CD8 2. Explain the previous question by select all the correct following options. How are CD8+ T cell responses against HIV induced? HIV antigens need to be ______. a. presented to CD8 T cells by B cells b. cross-presented c. presented to CD8 T cells by unnifected DCs d. delivered as a vaccinearrow_forwardUnlike cytotoxic T lymphocytes, NK cells do not _____. (Select all that apply.) a. secrete cytokines b. participate in the adaptive immune response c. rearrange T-cell receptor genes d. use MHC class I molecules for their development and function e. express CD3 components.arrow_forwardA single antigen molecule contains multiple ________. A. T-cell receptors B. B-cell receptors C. MHC II D. Epitopesarrow_forward
- The high degree of polymorphism in MHC class I molecules that present antigens to CD8 T cells is found in _______ because _______ is/are monomorphic: a. β2-microglobulin; the heavy chain b. both the α and β chains; none c. HLA-DOβ; HLA-DOα d. the heavy chain; β2-microglobulin e. HLA-E and HLA-G; HLA-F.arrow_forwardA number of minor cancerous cells and infected viruses, such as Epstein Barr (EBV), are able to go undetected by cytotoxic T cell degradation by what possible mechanism? a. the production of normal class I MHC molecule b. helper T cell activation c. the deactivation of the complement system d. tumor antigen expression e. the production of the class II major histocompatability (MHC) moledulearrow_forwardWhich of the following statements regarding CD1 is correct? a. CD1 binding grooves are very similar to those of MHC class I molecules. b. Lipid antigens of CD1 bind with high affinity and are rarely exchanged. c. CD1 comprises three MHC class I-like heavy chains known as CD1c, CD1d, and CD1e, each belonging to a different functional group. d. CD1 molecules form heterodimers with β2-microglobulin. e. When a CD1d molecule presents sulfatide to a γ:δ T cell, all three CDR loops of both the γ and δ chains must be engaged to activate the T cell. f. CD1 genes are located in the HLA complex on chromosome 6.arrow_forward
- Which of the following is part of the second line of defense against pathogens?a. skin b. mucus membranesc. lysozyme in tears d. phagocytes Which of the following does NOT have MHC class II molecules on the surface of their cell membranes? a. Macrophages.b. Dendritic cells.c. B cells.d. Helper T cells.arrow_forwardThe binding groove of endothelial protein C receptor (EPCR) binds to _____ and presents them to _____. a. phosphoantigens; Vγ9:Vδ2 T cells b. MIC-A or MIC-B proteins; NK cells c. sulfatides; Vγ:Vδ1 T cells d. phospholipids; Vγ4:Vδ5 T cells e. lipid antigens; Vα24–Jα18:Vβ11 NKT cells.arrow_forwardWhich of the following statements about T cells is false? a. Helper T cells release cytokines while cytotoxic T cells kill the infected cell. b. Helper T cells are CD4+, while cytotoxic T cells are CD8+. c. MHC II is a receptor found on most body cells, while MHC I is a receptor found on immune cells only. d. The T cell receptor is found on both CD4+ and CD8+ T cells.arrow_forward
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