EP MICROBIOLOGY:W/DISEASES BY..-MOD.ACC
5th Edition
ISBN: 9780134607894
Author: BAUMAN
Publisher: PEARSON CO
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 16, Problem 4CT
Scientists can develop genetically deficient strains of mice. Describe the immunological impairments that would result in mice deficient in each of the following: class I MHC, class II MHC, TCR, BCR, IL-2 receptor, and IFN-γ.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Describe the term "in-frame" and also the reason that it would be necessary for the generation of diversity in antigen receptors.
1:Describe the various stages of T cells and the events that occur during each of these stages during T cell development. What stages of T cell development would be affected in mice with the following genetic mutations? Justify your answer.
a) Mice that do not express MHC Class I molecule.
b) Mice that do not express Rag1
c) Mice that do not express the pre-T-alpha chain
2:Transgenic mice that have constitutive expression of Rag1/2 are being used in an experiment to study pre-BCR signaling. Based on your knowledge of early B cell development, speculate on what might be the fate of BCR rearrangement and how will this affect further development of B cells in the bone marrow?
please answer in full detail I want long well explained answers.
Name two ways in which the presence of antibodies enhances phagocytosis.
Chapter 16 Solutions
EP MICROBIOLOGY:W/DISEASES BY..-MOD.ACC
Ch. 16 - Why are the activities of B and T cells called...Ch. 16 - Why are exogenous epitopes processed in vesicles...Ch. 16 - Why did scientists give the name perforin to a...Ch. 16 - Plasma cells are vital for protection against...Ch. 16 - Microsporidiosis Darius is sick, which is not...Ch. 16 - Why is passive immunity effective more quickly...Ch. 16 - Prob. 1MCCh. 16 - Prob. 2MCCh. 16 - Rejection of a foreign skin graft is an example of...Ch. 16 - An autoantigen is ________________. a. an antigen...
Ch. 16 - Among the key molecules that control cell-mediated...Ch. 16 - Which of the following lymphocytes predominates in...Ch. 16 - Prob. 7MCCh. 16 - Which cells express MHC class I molecules in a...Ch. 16 - In which of the following sites in the body can B...Ch. 16 - Tc cells recognize epitopes only when the latter...Ch. 16 - Prob. 1MTFCh. 16 - Prob. 2MTFCh. 16 - Prob. 3MTFCh. 16 - Prob. 4MTFCh. 16 - Prob. 5MTFCh. 16 - Match each cell in the left column with its...Ch. 16 - Match each type of immunity in the left column...Ch. 16 - Label the parts of the immunoglobulin below.Ch. 16 - The nearby image is a transmission electron...Ch. 16 - When is antigen processing an essential...Ch. 16 - Why does the body have both antibody and...Ch. 16 - Why is it advantageous for the lymphatic system to...Ch. 16 - Contrast innate defenses with adaptive immunity.Ch. 16 - How does requiring the immune system to process...Ch. 16 - Scientists can develop genetically deficient...Ch. 16 - Human immunodeficiency virus (HIV) preferentially...Ch. 16 - What would happen to a person who failed to make...Ch. 16 - Prob. 7CTCh. 16 - Some materials, such as metal bone pins and...Ch. 16 - Prob. 9CTCh. 16 - The cross-sectional area of the afferent lymphatic...Ch. 16 - Two students are studying for an exam on the bodys...Ch. 16 - In general, what sorts of pathogens might be able...Ch. 16 - What sorts of pathogens could successfully attack...Ch. 16 - As part of the treatment for some cancers,...Ch. 16 - Prob. 1CM
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Describe the development of antibodies to a specificantigen.arrow_forwardInfants and young children with deficiencies in specific complement components present with recurrent respiratory infections caused by extracellular bacteria. The peak age of susceptibility is between 6 and 12 months after birth. At this time, as shown in figure below, maternal antibodies acquired by the child during fetal gestation are nearly gone, but the child is not yet generating robust antibody responses to new infections, as indicated by the low circulating levels of IgG and IgA. As children with this immunodeficiency get older, they outgrow this disease and show no further evidence of these recurrent infections. Based on this information, name one likely gene deficiency (in the complement system) that could cause this primary immunodeficiency, and the specific complement pathway likely to be affected. Explain your answer.arrow_forwardName two antigen-presenting cells. What is their role in the adaptive immune system? Which classes of MHC proteins do they express and why is this important?arrow_forward
- Describe and give one example: artificial active acquired immunity artificial passive acquired immunity natural active acquired immunity natural passive acquired immunityarrow_forwardDefine polymorphism and polygeny as they apply to MHC genes.arrow_forwardHow are antibodies unique? Please discuss the structure of an antibody. What are the V and C regions? Discuss how the few hundred genes involved are capable of making endless amounts of antibodies. Besides medical treatment what is another way antibodies can be used?arrow_forward
- Describe Class I MHC pathway of antigen processing and presentation. Highlight the functions of the structures and organelles associated with the pathway. Illustrate with a diagram.arrow_forwardWhat is an introduction to ANTIBODY STRUCTURE AND FUNCTION ? How would you summarize this to someone who is new to this? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726606/arrow_forwardDescribe the significance and need for receptor editing as a part of elimination of self-reactive B lymphocytes.arrow_forward
- What is MHC? List the specific cells that have MHC presentation and describe their role in the immune response.arrow_forwardPeptides are stably bound to MHC molecules, and also serve to stabilize the MHC molecule on the cell surface. Once expressed on the surface of host cells, an MHC protein remains stably associated with its bound peptide for several days. This highly stable peptide binding behavior is important because: a) It prevents peptide exchanges on the cell surface, ensuring that peptide:MHC complexes are reliable indicators of the proteins present inside that host cell. b) If the MHC protein lost its peptide it would become unstable, and would be rapidly internalized and degraded. c) Pathogens would otherwise evade the immune response by making decoy peptides that mimic host cell peptides. d) Pathogens would be able to evade the T cell response by making proteases that cleave MHC proteins inducing peptide release. e) Immune responses to infection often induce noxious chemicals that damage surface MHC proteins, and might result in peptide loss.arrow_forwardWhich of the followings is molecular pathology associated with ADA mutations that cause immunodeficiency? a) accumulation of deoxyadenosine and its precursors S-adenosylhomocysteine and deoxyadenosine triphosphate (dATP) with toxic effects on immature lymphocytes, b)accumulation of deoxyguanosine and deoxyguanosine triphosphate, with toxic effects on immature lymphocytesarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax CollegeHuman Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningHuman Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
- Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Immune System and Immune Response Animation; Author: Medical Sciences Animations;https://www.youtube.com/watch?v=JDdbUBXPKc4;License: Standard YouTube License, CC-BY
Immune response: summary; Author: Dr Bhavsar Biology;https://www.youtube.com/watch?v=ADANgHkX4OY;License: Standard Youtube License