EBK PRINCIPLES OF HUMAN PHYSIOLOGY
6th Edition
ISBN: 8220101472250
Author: STANFIELD
Publisher: PEARSON
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Chapter 15, Problem 3E
Summary Introduction
Introduction :
Leukocytes, also known as White Blood Cells (WBCs), are one of the major constituents of blood. The main function of WBCs is to protect our body against any infection and foreign invasion. These are of five different types − Neutrophils, Eosinophils, Basophils, Monocytes, and Lymphocytes.
Phagocytosis is a process like endocytosis in which the cell engulfs a large particle that gives rise to an internal compartment known as a phagosome.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 15 Solutions
EBK PRINCIPLES OF HUMAN PHYSIOLOGY
Ch. 15.3 - Prob. 15.1.1QCCh. 15.3 - Prob. 15.1.2QCCh. 15.3 - Prob. 15.1.3QCCh. 15.3 - Prob. 15.1.4QCCh. 15.4 - Prob. 1CTQCh. 15.4 - Prob. 2CTQCh. 15.4 - Prob. 3CTQCh. 15.4 - Prob. 15.2.1QCCh. 15.4 - Prob. 15.2.2QCCh. 15.4 - Prob. 15.2.3QC
Ch. 15 - Prob. 1ECh. 15 - Which organ synthesizes...Ch. 15 - Which of the following classes of leukocytes...Ch. 15 - Which class of leukocytes develops into...Ch. 15 - Prob. 5ECh. 15 - Prob. 6ECh. 15 - Prob. 7ECh. 15 - Prob. 8ECh. 15 - Describe the life cycle of erythrocytes. Be sure...Ch. 15 - Prob. 10ECh. 15 - Prob. 11ECh. 15 - Prob. 12E
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