BIOCHEMISTRY
BIOCHEMISTRY
9th Edition
ISBN: 2818440090622
Author: BERG
Publisher: MAC HIGHER
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Chapter 15, Problem 25P
Interpretation Introduction

Interpretation:

The ratio of (B/A) under cellular condition is to be calculated.

Concept introduction:

ATP is a nucleotide that consists of adenine, ribose and a triphosphate unit.

When ATP is hydrolyzed to adenine monophosphate and pyrophosphate, a large amount of energy is liberated.

A can be converted into B under these conditions if the reaction is coupled to the hydrolysis of ATP. The overall reaction is as follows:

A+ATP+H2OB+ADP+Pi

The equilibrium constant expression for the coupled reaction is as follows:

Keq'=( [B] eq [A] eq)( [ ADP] eq [ P 1 ] eq [ ATP] eq)   ....... (1)

Where,

  • Keq' is the equilibrium constant.
  • [B]eq is the concentration of B at equilibrium.
  • [A]eq is the concentration of A at equilibrium.
  • [ADP]eq is the concentration of ADP at equilibrium.
  • [ATP]eq is the concentration of ATP at equilibrium.
  • [P1]eq is the concentration of P1 at equilibrium.

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