Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 14, Problem 7P
Suppose you are characterizing the DNA of a diploid plant species that had never been analyzed previously.
You purify all the DNA that can be isolated from a seedling, and subject this DNA to high-throughput sequencing involving millions of “reads” of random DNA fragments.
| a. | If you obtained on average 100 reads of a given single-copy nuclear DNA sequence, about how many reads would you obtain for mtDNA? For cpDNA? (Assume each mitochondrion has 10 ge- nome copies and that each choloroplast has 20 ge- nome copies. Assume also that the average cell of this plant species has 1000 mitochondria and 50 chloroplasts.) |
| b. | Beyond the number of reads, what other criteria would allow you to conclude whether a particular read was of nuclear DNA, mtDNA, or cpDNA? |
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Case Study—Ella
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
Categories of Sandwich Options (Top of the screen)
Breads
Spreads
Cheeses
Vegetables
Proteins
Specific food items to select
White Bread 6-inches
Honey Mustard
Provolone
LettuceTomatoBell Peppers
Turkey
Part A - Reading Nutrition Facts Panels for Total Kilocalories
How many total kilocalories are in Ella’s sandwich exactl ______kcal ?
Part B - Reading Nutrition Facts Panels for…
C
MasteringHealth MasteringNu ×
session.healthandnutrition-mastering.pearson.com/myct/itemView?assignment ProblemID=17465255&attemptNo=1&offset=prev
Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Chapter 14 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 14 - Match each numbered item with the most closely...Ch. 14 - Assuming human cells have on average 1000...Ch. 14 - Reverse translation is a term given to the process...Ch. 14 - The human nuclear genome encodes tRNAs with 32...Ch. 14 - The human mitochondrial genome includes no genes...Ch. 14 - Is each of these statements true of chloroplast or...Ch. 14 - Suppose you are characterizing the DNA of a...Ch. 14 - An example of a cloning vector used for biolistic...Ch. 14 - Which of the following characteristics of...Ch. 14 - The Saccharomyces cerevisiae nuclear gene ARG8...
Ch. 14 - The so-called hypervariable regions HV1 and HV2 of...Ch. 14 - Suppose a new mutation arises in a mitochondrial...Ch. 14 - Describe at least two ways in which the...Ch. 14 - Why are severe mitochondrial or chloroplast gene...Ch. 14 - Suppose you are examining a newly found plant...Ch. 14 - A form of male sterility in corn is inherited...Ch. 14 - Plant breeders have long appreciated the...Ch. 14 - Prob. 18PCh. 14 - Prob. 19PCh. 14 - What characteristics in a human pedigree suggest a...Ch. 14 - The first person in the family represented by the...Ch. 14 - In 1988, neurologists in Australia reported the...Ch. 14 - If you were a genetic counselor and had a patient...Ch. 14 - Kearns-Sayre syndrome KSS, Pearson syndrome, and...Ch. 14 - Prob. 25PCh. 14 - Prob. 26P
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