Biology
12th Edition
ISBN: 9781260494570
Author: Raven, Peter
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Textbook Question
Chapter 14, Problem 5A
If the activity of DNA ligase was removed from replication, this would have a greater effect on
a. synthesis on the lagging strand versus the leading strand.
b. synthesis on the leading strand versus the lagging strand.
c. priming of DNA synthesis versus actual DNA synthesis.
d. photorepair of DNA versus
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Students have asked these similar questions
During DNA replication, short RNA primers are made by the Primase. Why?
a.
To provide a 3'-OH so DNA polymerase can begin DNA synthesis.
b.
To recruit single stranded binding proteins to the correct location.
c.
To identify the termination sequence for DNA polymerase during DNA synthesis.
d.
To provide a 3'-OH so RNA polymerase can begin DNA synthesis.
e.
To identify the origin of replication to recruit the origin replication complex to the correct genomic location.
Strand invasion is often used to repair which of the following damages to DNA?
a.
Single-strand breaks
b.
Double-strand breaks.
c.
Mismatched bases
d.
Thymine dimers.
Which statement about Okazaki fragments is true?
Select one:
a. DNA polymerase doesn’t need a primer to build these fragments
b. They act as a primer that initiates DNA replication.
c. They correct errors made during earlier phases of DNA replication.
d. They are necessary because DNA polymerase can only build DNA in the 5’ to 3’ direction, so for one of the strands at each fork, the DNA polymerase can only buildaway from the fork.
e. They prevent the ends of chromosomes from shortening with every replication.
Chapter 14 Solutions
Biology
Ch. 14.1 - Describe the experiments of Griffith and Avery.Ch. 14.1 - Evaluate the evidence for DNA as genetic material.Ch. 14.2 - Explain how the WatsonCrick structure rationalized...Ch. 14.2 - Prob. 2LOCh. 14.3 - Prob. 1LOCh. 14.3 - Prob. 2LOCh. 14.4 - Prob. 1LOCh. 14.4 - Prob. 2LOCh. 14.4 - Diagram the functions found at the replication...Ch. 14.5 - Compare eukaryotic replication with prokaryotic.
Ch. 14.5 - Prob. 2LOCh. 14.5 - Prob. 3LOCh. 14.6 - Prob. 1LOCh. 14.6 - Prob. 2LOCh. 14 - Prob. 1DACh. 14 - Prob. 2DACh. 14 - Prob. 1IQCh. 14 - Prob. 2IQCh. 14 - How does the structure of eukaryotic genomes...Ch. 14 - Prob. 4IQCh. 14 - Prob. 1UCh. 14 - Which of the following is NOT a component of DNA?...Ch. 14 - Chargaff studied the composition of DNA from...Ch. 14 - The bonds that hold two complementary strands of...Ch. 14 - Prob. 5UCh. 14 - Prob. 6UCh. 14 - Which of the following is NOT pan of the...Ch. 14 - If one strand of a DNA is 5 ATCGTTAAGCGAGTCA 3,...Ch. 14 - Hershey and Chase used radioactive phosphorus and...Ch. 14 - The Meselson and Stahl experiment used a density...Ch. 14 - Prob. 4ACh. 14 - If the activity of DNA ligase was removed from...Ch. 14 - Successful DNA synthesis requires all of the...Ch. 14 - The synthesis of telomeres a. uses DNA polymerase,...Ch. 14 - When mutations that affected DNA replication were...Ch. 14 - Prob. 1SCh. 14 - In the Meselson-Stahl experiment, a control...Ch. 14 - Enzyme function is critically important for the...
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- Determine whether each statement isTRUE or FALSE.a. In eukaryotic chromosomes, DNA replication begins at a single point in the chromosome and proceeds in two directions.b. The bonds between the sugars and phosphates are broken during DNA replication.c. The elongation of the leading strand during DNA synthesis progresses away from the replication fork.d. Each DNA molecule resulting from replication has one original strand and one new strand.e. The difference in how the leading and lagging strands of DNA molecules are synthesized is due to DNA polymerase adding new nucleotides only to the 3’ end of a growing strand, and the strands are anti-parallel.arrow_forwardThe function of DNA ligase is to: a. Catalyze formation of phosphodiester bonds between adjacent nucleotides b. Catalyze formation of hydrogen bonds between adjacent nucleotides c. Keep single strands of DNA apart during replication d. Facilitate base pairing between single stranded molecules in DNA e. Both a. and d. are correctarrow_forwardFor the statements below, indicate whether the statement applies to the leading strand, or to the lagging strand, or to both. a. synthesized in the 5'→3' direction b. synthesized continuously c. require(s) DNA ligase to join fragments d. described as a daughter strand e. synthesized in the same direction as the movement of the replication fork f. DNA polymerase is the enzyme involved in forming this polynucleotide.arrow_forward
- Match the enzymes provided from (1-4) in the list of choices with their matching function (A-D) during DNA replication. A. Disrupts hydrogen bonds between DNA bases B. Can only add nucleotides to an existing 3 OH end C. Can't add nucleotides to a chain, but can make covalent bonds D. Actually a specialized form of RNA polymerase select 1. DNA polymerase select 2. Primase select 3. Ligase select v 4. Helicasearrow_forwardThe enzyme responsible for adding new nucleotides to a growing DNA chain during DNA replication is a. helicase. b. RNA polymerase. c. DNA polymerase. d. DNA ligase.arrow_forwardDuring DNA replication, DNA methylation: please explain answer a. A and C b. B. marks the strand not cut in mismatch repair c. A and B d. A. marks the parental DNA strand e. C. marks the strand cut in mismatch repairarrow_forward
- During DNA replication: A. The two DNA strands separate, each strand then becomes a template for the assembly of a complementary strand. Each new DNA helix has one old strand with one new strand. B. The two DNA strands separate, each strand then becomes a template for the assembly of a similar strand. Each new DNA helix has one old strand with one new strand. C. The two DNA strands separate, each strand then becomes a template for the assembly of a similar strand. Each new DNA helix has two new strands. D. The two DNA strands separate, each strand then becomes a template for the assembly of an identical strand. Each new DNA helix has one old strand with one new strand.arrow_forwardWhich of the following is not a true statement comparing prokaryotic and eukaryotic DNA replication? a. Both eukaryotic and prokaryotic DNA polymerases build off RNA primers made by primase. b. Eukaryotic DNA replication requires multiple replication forks, while prokaryotic replication uses a single origin to rapidly replicate the entire genome. c. DNA replication always occurs in the nucleus. d. Eukaryotic DNA replication involves more polymerases than prokaryotic replication.arrow_forwardWhich of the following statements accurately describes the process of DNA replication? A. The two strands of DNA separate, and a single new strand is synthesized using the existing strand as a template. B. The two strands of DNA separate and serves as a template, and the daughter molecule will have a mix of an old and new strand. C. The two strands of DNA separate and serves as a template, and the daughter molecule will have one old strand and one new strand. D. The two strands of DNA separate, and each strand serves as a template for the synthesis of multiple new complementary strands.arrow_forward
- when a cell to divide, its DNA must be replicated (copied). a.List the most important participating components and their functions in replication b.why is it important that the replication goes right and that relatively few mutations occur during the replication? c.Will the offspring of the individual who received a mutation inherit the mutationarrow_forwardDuring DNA replication, which of the following steps occurs first? a. synthesis of the leading strand b. synthesis of the lagging strand c. unwinding of the parental DNA duplex d. sealing of the nicks between short DNA e. synthesis of primersarrow_forwardIn nucleotide excision repair in E. coli, the function of the UvrA/UvrB complex is toa. detect DNA damage.b. make cuts on both sides of the damage.c. remove the damaged piece of DNA.d. replace the damaged DNA with undamaged DNA.arrow_forward
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