Evolution
Evolution
4th Edition
ISBN: 9781605356051
Author: Douglas Futuyma, Mark Kirkpatrick
Publisher: SINAUER
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Chapter 14, Problem 4PDT
Summary Introduction

To explain: The possible reasons for the movement of genetic loci from the X chromosome to autosomes in Drosophila.

Introduction: Gene trafficking refers to the movement of genes from one site to another site. Deletion plays a key role in the process of gene trafficking. Parental copy of the gene may get lost due to deletion. Gene trafficking has been observed in Drosophila where genes moved from X chromosomes to autosomes.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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