Evolution
4th Edition
ISBN: 9781605356051
Author: Douglas Futuyma, Mark Kirkpatrick
Publisher: SINAUER
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Chapter 14, Problem 2PDT
Summary Introduction
To determine: The specific data required to detect the situation using dN/dS ratio in the case of paralogs and the pattern observed in duplicative loci using the dN /dS ratio.
Introduction: The origin of two or more genes arising from the process of duplication are said to be paralogs. A hemoglobin gene family is composed of many paralogs which are separated in due course of time. The importance of positive selection can be studied with the help of a simple statistical method (dN/dS) comprising of DNA sequences from two different species.
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If PCR was performed on the fragment of DNA shown below using "5'-TAGG-3" and "3'-TCTA-5'" as the primers, how many base pairs long would the PCR product be? To help with this, remember the antiparallel structure of DNA and that primers are complementary and antiparallel to the target sequence that they bind to. Hint: Check out the 5' and 3' labels....they are important!
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Evolution
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