Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 14, Problem 4P

Bacterial genomes such as that of E. coli typically have only a single origin of replication, from which replication proceeds bidirectionally. Pol III, the DNA polymerase responsible for replicating the E. coli chromosome, synthesizes DNA at a rate of about 1000 nucleotides per second.

a. From this information, estimate the minimum generation time of E. coli.
b. Under optimal conditions, E. coli have been observed to divide in as little as 17 minutes. Speculate how this
Might be possible, given your answer to part (a).
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Genetics: From Genes to Genomes

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