Concepts of Genetics (11th Edition)
Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 14, Problem 39ESP

(a)

Summary Introduction

To determine: The class of amino acids that reside on the surface of a protein within a cell.

Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

(b)

Summary Introduction

To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

(c)

Summary Introduction

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

(d)

Summary Introduction

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

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Concepts of Genetics (11th Edition)

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Macromolecules | Classes and Functions; Author: 2 Minute Classroom;https://www.youtube.com/watch?v=V5hhrDFo8Vk;License: Standard youtube license