The class of amino acids that reside on the surface of a protein within a cell. Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

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Answer 1

Question

Chapter 14, Problem 39ESP

(a)

Summary Introduction

To determine: The class of amino acids that reside on the surface of a protein within a cell.

Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

(b)

Summary Introduction

To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

(c)

Summary Introduction

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

(d)

Summary Introduction

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

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Answer 2

Question

Chapter 14, Problem 39ESP

(a)

Summary Introduction

To determine: The class of amino acids that reside on the surface of a protein within a cell.

Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

(b)

Summary Introduction

To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

(c)

Summary Introduction

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

(d)

Summary Introduction

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

Expert Solution & Answer

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Answer 3

Question

Chapter 14, Problem 39ESP

(a)

Summary Introduction

To determine: The class of amino acids that reside on the surface of a protein within a cell.

Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

(b)

Summary Introduction

To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

(c)

Summary Introduction

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

(d)

Summary Introduction

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

Expert Solution & Answer

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Answer 4

Question

Chapter 14, Problem 39ESP

(a)

Summary Introduction

To determine: The class of amino acids that reside on the surface of a protein within a cell.

Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

(b)

Summary Introduction

To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

(c)

Summary Introduction

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

(d)

Summary Introduction

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

Expert Solution & Answer

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Answer 5

Chapter 14, Problem 39ESP

(a)

Summary Introduction

To determine: The class of amino acids that reside on the surface of a protein within a cell.

Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

(b)

Summary Introduction

To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

(c)

Summary Introduction

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

(d)

Summary Introduction

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

Answer 6

Chapter 14, Problem 39ESP

(a)

Summary Introduction

To determine: The class of amino acids that reside on the surface of a protein within a cell.

Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

Answer 7

Chapter 14, Problem 39ESP

(a)

Summary Introduction

To determine: The class of amino acids that reside on the surface of a protein within a cell.

Introduction: Proteins are the building blocks of animals. It is a high molecular weight compound that is also called macromolecule. The shape and structure of proteins have a role in its function. Proteins have four levels of the structural organization namely, primary, secondary, tertiary and quaternary structures. The quarternary structure of a protein is maintained or stabilized by various interactions such as hydrogen-bonding, disulfide-bridges, and salt bridges.

Answer 8

(b)

Summary Introduction

To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

Answer 9

(b)

Summary Introduction

To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

Answer 10

(c)

Summary Introduction

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

Answer 11

(c)

Summary Introduction

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

Answer 12

(d)

Summary Introduction

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

Answer 13

(d)

Summary Introduction

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

Answer 14

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Answer 15

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Answer 16

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Answer 17

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To determine: The amino acid sequence that is likely to be effective in blocking the functional site of a receptor molecule that consists of glutamate, arginine, and aspartate at the functional site.

To determine: Why D-amino acid stereoisomers are especially useful for inhibiting a functional site of the androgen receptor.

To determine: How the knowledge of protein structure is used in designing rational drug compared to classical trial-and-error approach.

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