Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781259709227
Author: Marjorie Kelly Cowan Professor, Heidi Smith
Publisher: McGraw-Hill Education
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Chapter 14, Problem 2Q
Can you think of a reason why humans have evolved to mount an immune response to their own fetuses if they have a particular set of foreign antigens (as in the case of erythroblastosis fetalis)?
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Some primitive organisms, such as invertebrates, have no lymphocytes and thus lack an adaptive immune system, but they have somecomponents of an innate immune system, including phagocytes andcertain protective proteins. What are some general features of innateimmunity that make it very valuable to organisms lacking more specific antibody- and cell-mediated responses? What are some disadvantages to having only an innate immune system?
Herd immunity means that the entire population (not just those who are vaccinated) are protected from a disease. What is one way that herd immunity protects an unvaccinated person (such as an infant who is too young to be vaccinated or a person who is immunocompromised)?
Determine the reason as to why humans have evolved to mount an immune response to their own fetuses if they have a particular set of foreign antigens as in the case of erythroblastosis fetalis.
Chapter 14 Solutions
Microbiology Fundamentals: A Clinical Approach
Ch. 14.1 - Define immunopathology, and identify the two major...Ch. 14.1 - Identify the four major categories of...Ch. 14.2 - Summarize genetic and environmental factors that...Ch. 14.2 - Identify three conditions caused by IgE-mediated...Ch. 14.2 - Identify the two clinical forms of anaphylaxis,...Ch. 14.2 - List the three main ways to prevent or...Ch. 14.2 - NCLEX PREP 1. During a visit to his physician, a...Ch. 14.2 - Prob. 2NPCh. 14.3 - List the three immune components causing cell...Ch. 14.3 - Prob. 8AYP
Ch. 14.4 - Prob. 9AYPCh. 14.4 - Medical Moment Patch Testing Patch testing is an...Ch. 14.5 - Prob. 10AYPCh. 14.5 - List four classes of grafts, and explain how host...Ch. 14.5 - NCLEX PREP 3. A patient receives a kidney...Ch. 14.6 - List at least three autoimmune diseases and the...Ch. 14.7 - Distinguish between primary and secondary...Ch. 14.7 - Medical Moment Hand Washing The importance of hand...Ch. 14.7 - Prob. 4NPCh. 14 - Allergy and atopy might have evolved in human...Ch. 14 - Can you think of a reason why humans have evolved...Ch. 14 - Prob. 3QCh. 14 - Prob. 4QCh. 14 - What feature of antibodies makes them particularly...Ch. 14 - Prob. 6QCh. 14 - Prob. 7QCh. 14 - Prob. 8QCh. 14 - Epi-pens are devices used to instantly inject a...Ch. 14 - Prob. 10QCh. 14 - Steroids administered to stop an allergic response...Ch. 14 - A very small number of people have a condition...Ch. 14 - Prob. 13QCh. 14 - Prob. 14QCh. 14 - Recent research shows that asthmatic patients have...Ch. 14 - Which statement is true of autoimmunity? a. It...Ch. 14 - It is often said that the normal microbiota of a...Ch. 14 - Investigate the link between Streptococcus...Ch. 14 - Which disease would be most similar to AIDS in its...Ch. 14 - Do you think people with B-cell deficiencies can...Ch. 14 - The chapter tells us that the gut microbiome of...Ch. 14 - Prob. 1VC
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- What scenario best describes an autoimmune reaction? Group of answer choices The destruction of donated red blood cells by the recipient’s immune system The production of antibodies against Streptococcus pyogenes antigen resulting in cross-reaction against an antigen found on heart valves The activation of Mast cells by pollen The production of antibodies against Streptococcus pyogenes resulting in the deposit of antigen-antibodies in the kidney leading to glomerulonephritisarrow_forwardGranzyme and perforin are used by what cell type in the immune system to carry out its function? O 1) TH1 O 2) Neutrophil 3) Cytotoxic T cell O 4) Eosinophilarrow_forwardApproximately 70% of the body’s immune system cells are located in or near the wall of the lower intestinal tract (intestines). Can you suggest a reason for this phenomenon?arrow_forward
- Sponges display nonspecific immunity. In an experiment, the cells of two different sponges were mixed and placed within a petri dish. The cells from each sponge sorted and arranged themselves together according to organism. What does this characteristic demonstrate? A. Sponges have memory T-cells and share a more recent common ancestor with vertebrates than other invertebrates. B. The experiment provides evidence for the speed of evolution and the use of specific immunity within the organism. C. Sponges have an ability to recognize their own cells as a characteristic of acquired immunity. D. Sharing genetic information from cell to cell is possible by means of receptors and protein-lined pits.arrow_forwardpicture 1 shows the directed migration of two immune cell types, neutrophils (red) and macrophages (green) to a laser-induced injury in the ear of a mouse. As you can observe from the video, there are three stages to this process: 1) an initial phase characterized by fast recruitment of neutrophils (red) to the site of injury followed by 2) the slower recruitment of macrophages after which 3) the interaction between both cell types is stabilized. Recruitment to the injury site is mediated by leukotriene B4 (LTB4), a potent immune signaling molecule (Figure 1A). LTB4 binds to BLT1, a G-protein coupled receptor (GPCR), activating various signaling pathways and resulting in immune cell migration to the site of injury (Figure 1B). With this background information and your knowledge of cell and molecular biology, describe in detail in your own words, as many molecular processes as you can identify that must take place for the cell migration process depicted in the video to be achieved. For…arrow_forwardFigure 17.17 The Rh antigen is found on Rh-positive red blood cells. An Rh-negative female can usually carry an Rh-positive fetus to term without difficulty. However, if she has a second Rh-positive fetus, her body may launch an immune attack that causes hemolytic disease of the newborn. Why do you think hemolytic disease is only a problem during the second or subsequent pregnancies?arrow_forward
- This term describes an antigen that is too small to be immunogenic, however it binds to proteins in the body to increase its size, allowing it to then be able to trigger an immune reaction: O 1) hapten O 2) alloantigen 3) superantigen O 4) epitopearrow_forwardHuman immune system a) Pathogen-associated molecular patterns are conserved molecular structures produced by microorganisms, but not by host cells. b) A virus-infected host cell that displays a viral antigen via MHC class I molecules may become a target of cytotoxic T cells. c) Secreted MHC Class I proteins present in blood plasma can function as opsonins. d) Both (a) and (b) are correct and (c) is incorrect e) Statements (a), (b) and (c) are all correctarrow_forwardWhich of the following should be the same inidentical twins?(A) the set of antibodies produced(B) the set of MHC molecules produced(C) the set of T cell antigen receptors produced(D) the set of immune cells eliminated as self-reactivearrow_forward
- How are innate lymphoid cells, including natural killer cells, distinguished from lymphocytes? a- stimulation by pathogen associated molecular patterns b- single lobed nucleus c- production of cytokines d-expression of rearranged antigen receptorsarrow_forwardWhat is a cytokine? A ) a. a chemical mediator (stimulus) of inflammation that is released by cells in response to tissue or cell damage O b. an antimicrobial substance made by neutrophils O c. a repair stimulator produced by Eosinophils during an allergic reaction O d. cellular (cyto-) substance that mediates noisy arguments between macrophages and lymphocytes And that I put A Cardiac disease is considered a(n) O a. acute, 3 O b. acute, 10 1 c. chronic, 3 O d. chronic, 10 Oe, acutely chronic, 114 And that I put Chronic 3 Are the 3 questions correct?arrow_forwardWhat are CD4 lymphocytes? What is the relationship between these cells and HIV? How does HIV replicate?arrow_forward
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