Biochemistry, The Molecular Basis of Life, 6th Edition
Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 14, Problem 29RQ
Summary Introduction

To review:

The series of reactions thatshow the role of pyridoxal phosphate in the reaction of alanine and α-ketoglutarate.

Introduction:

Transamination can be characterized by the transfer of α-amino groups from α-amino acid to α-keto acid. This reaction is catalyzed by aminotransferase enzyme, which is also called transaminase. In this reaction, the keto acid acts as the acceptor while the amino acid acts as the donor of amino group. This results in the formation of a new amino acid and a new keto acid. Such reactions require a coenzyme called PLP (pyridoxal-5’-phosphate). This enzyme is derived from a vitamin B6, pyridoxine.

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Biochemistry What is the process of "transamination" in either the muscles or the liver, that involves keto acid or glutamic acid? Please explain how the steps work. Thank you!
Biochemistry Please help. Thank you What is the importance of glutamic acid in the metabolism of nitrogen from amino acids? (we know therole; it’s used to remove the nitrogen from amino acids so that the remaining carbon skeleton can bebroken down by the “usual” pathways, but what is the important, unique role that only glutamicacid/glutamate can do?)
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