Chapter 14, Problem 1GP

Summary Introduction

To explain: Duchenne muscular dystrophy occurs almost exclusively in males.

Introduction:

Duchenne muscular dystrophy (DMD) is a genetic disorder caused by the mutation of the dystrophin gene. It is located on X chromosome. The dystrophin protein is found in the skeletal and cardiac muscles that provide strength to muscle fibers and connect cytoplasm in the muscle cells to the extracellular matrix. The mutation in the gene results in defective dystrophin protein causing muscle degeneration. DMD is a recessive X-linked condition.