Biology
4th Edition
ISBN: 9781259188121
Author: Peter Stiling, Robert Brooker, Linda Graham, Eric Widmaier
Publisher: McGraw-Hill Education
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Question
Chapter 13.6, Problem 2CC
Summary Introduction
To determine: The way by which IRP protect people from toxic effects of too much iron.
Introduction: Iron is an important cofactor for various types of cellular enzymes but is toxic at elevated concentrations. For the prevention of toxic effects, some proteins are synthesized in mammalian cells which reduce the toxic level of proteins.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 13 Solutions
Biology
Ch. 13.1 - Prob. 1CCCh. 13.2 - Which genes are under the control of the lac...Ch. 13.2 - With regard to regulatory proteins and small...Ch. 13.2 - What were the key observations made by Jacob,...Ch. 13.2 - CoreSKILL What was the eventual hypothesis...Ch. 13.2 - Prob. 3EQCh. 13.2 - Core Skill: Connections Look back at Fig 9.12....Ch. 13.2 - What are the advantages of having both an...Ch. 13.2 - Prob. 4CCCh. 13.4 - Prob. 1CC
Ch. 13.4 - Prob. 2CCCh. 13.4 - Prob. 1BCCh. 13.6 - Prob. 1CCCh. 13.6 - Prob. 2CCCh. 13 - Prob. 1TYCh. 13 - Prob. 2TYCh. 13 - Transcription factors that bind to DNA and...Ch. 13 - Prob. 4TYCh. 13 - For the lac operon, what would be the expected...Ch. 13 - Prob. 6TYCh. 13 - The trp operon is considered _____ blank operon...Ch. 13 - Prob. 8TYCh. 13 - Prob. 9TYCh. 13 - _____ blank refers to the process that allows a...Ch. 13 - Prob. 1CQCh. 13 - Transcriptional regulation often involves a...Ch. 13 - Prob. 3CQCh. 13 - Discuss the advantages and disadvantages of...Ch. 13 - Discuss the advantages and disadvantages of...
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