Campbell Biology in Focus, Books a la Carte Edition; Modified Mastering Biology with Pearson eText - ValuePack Access Card - for Campbell Biology in Focus (2nd Edition)
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Chapter 13.2, Problem 1CC

What role does base pairing play in the replication of DNA?

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a) Draw a DNA replication fork and label the polarity of your DNA (you decide which strand is 3’à5’ and 5’à3) and label the leading and lagging strand. Depict the helicase, topoisomerase, and SSBPs doing their jobs in early DNA replication as well as a primase on each strand laying down an RNA primer.   b) Describe the main jobs of each of the following enzymes in the coli model of replication: DNA Polymerase I  2. DNA Polymerase II    3. DNA Polymerase III
a) Use the codon chart to translate the following mRNA codons into amino acids: AUG GUU AAC CAG UGA   b) How do mRNA and rRNA interact?   c) How do mRNA and tRNA interact?
a. Describe the replisome   b. What is the “end problem of linear chromosomes” and what enzymeis used by some cells get around this issue?   c. Draw the rough shape of the sliding clamp. What is the point of this protein?
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