Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780321962751
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 13, Problem 2TYU
What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?
- A. DNA polymerase can join new
nucleotides only to the 3’ end of a preexisting strand. - B. Helicases and single-strand binding proteins work at the 5’ end.
- C. The origins of replication occur only at the 5’ end.
- D. DNA ligase works only in the 3’ → 5’ direction.
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Students have asked these similar questions
What is the correct chronological order of the initiation of DNA replication?
A. Hydrogen bonds between complementary base pairs are broken at origin of replication
B. Primase binds to the site of origin.
C. DNA polymerase binds to the template strand.
D. An RNA primer is synthesized.
E. Incoming deoxynucleoside triphosphates are added to the growing strand.
What was the significance of Meselson and Stahl’s experiments on DNA replication using the heavy isotope of Nitrogen?
A. telomerase was identified as the molecule responsible for solving the end replication problem of eukaryotic chromosomes
B. the existence of lagging strand synthesis was proven.
C. the rate of DNA synthesis by DNA polymerase was measured
D. the processivity of DNA polymerase was established
E. the semi-conservative mode of DNA replication was confirmed
Why are Okazaki fragments formed?
A. Okazaki fragments are the result of discontinuous replication due to the supersecondary
structure of the DNA
B. Okazaki fragments are the result of discontinuous replication resulting from the
polymerization that proceeds in the 5'-3' direction.
C. Okazaki fragments are the result of discontinuous replication resulting from the
polymerase having to wait for the primase to add primers so it can proceed in the 5'-3'
direction of synthesis.
D. Okazaki fragments are formed because endonucleases have to correct errors of
replication.
E. Okazaki fragments are formed when the 5'-3' complementary strand is the template for
replication.
Chapter 13 Solutions
Campbell Biology in Focus (2nd Edition)
Ch. 13.1 - Given a polynucleotide sequence such as GAATTC,...Ch. 13.1 - Prob. 2CCCh. 13.2 - What role does base pairing play in the...Ch. 13.2 - Make a table listing the functions of seven...Ch. 13.2 - MAKE CONNECTIONS What is the relationship between...Ch. 13.3 - Describe the structure of a nucleosome, the basic...Ch. 13.3 - What two properties, one structural and one...Ch. 13.4 - Prob. 1CCCh. 13.4 - DRAW IT One strand of a DNA molecule has the...Ch. 13.4 - Describe the role of complementary base pairing...
Ch. 13 - In his work with pneumonia-causing bacteria and...Ch. 13 - What is the basis for the difference in how the...Ch. 13 - In analyzing the number of different bases in a...Ch. 13 - The elongation of the leading strand during DNA...Ch. 13 - Prob. 5TYUCh. 13 - Prob. 6TYUCh. 13 - Prob. 7TYUCh. 13 - Prob. 8TYUCh. 13 - Prob. 9TYUCh. 13 - MAKE CONNECTIONS Although the proteins that cause...Ch. 13 - Prob. 12TYUCh. 13 - FOCUS ON EVOLUTION Some bacteria may be able to...Ch. 13 - FOCUS ON ORGANIZATION The continuity of life is...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In the dideoxy-sequencing reaction, what terminates DNA synthesis at a particular base? a. The absence of a base on the ddNTP halts the DNA polymerase. b. The ddNTP causes a break in the sugar–phosphate backbone. c. DNA polymerase will not incorporate a ddNTP into the growing DNA strand. d. The absence of a 3′-OH group on the ddNTP prevents the addition of another nucleotide.arrow_forwardWhich statement about Okazaki fragments is true? Select one: a. DNA polymerase doesn’t need a primer to build these fragments b. They act as a primer that initiates DNA replication. c. They correct errors made during earlier phases of DNA replication. d. They are necessary because DNA polymerase can only build DNA in the 5’ to 3’ direction, so for one of the strands at each fork, the DNA polymerase can only buildaway from the fork. e. They prevent the ends of chromosomes from shortening with every replication.arrow_forwardWhat describes or designates the 3' end of a DNA strand? a. an available hydroxyl group on the 5th carbon of a deoxyribose of a terminal nucleotide b. an available phosphate group on the 3rd carbon of a deoxyribose of a terminal nucleotide c. an available hydroxyl group on the 3rd carbon of a deoxyribose of a terminal nucleotide d. an available hydroxyl group on the 2nd carbon of a deoxyribose of a terminal nucleotidearrow_forward
- Which statement about Okazaki fragments is true? Select one: O a. They are necessary because DNA polymerase can only build DNA in the 5' to 3' direction, so for one of the strands at each fork, the DNA polymerase can only build away from the fork. O b. They correct errors made during earlier phases of DNA replication. O c. They act as a primer that initiates DNA replication. O d. They prevent the ends of chromosomes from shortening with every replication. e. DNA polymerase doesn't need a primer to build these fragments.arrow_forwardFor the statements below, indicate whether the statement applies to the leading strand, or to the lagging strand, or to both. a. synthesized in the 5'→3' direction b. synthesized continuously c. require(s) DNA ligase to join fragments d. described as a daughter strand e. synthesized in the same direction as the movement of the replication fork f. DNA polymerase is the enzyme involved in forming this polynucleotide.arrow_forwardWhat is the correct choicearrow_forward
- Match the enzymes provided from (1-4) in the list of choices with their matching function (A-D) during DNA replication. A. Disrupts hydrogen bonds between DNA bases B. Can only add nucleotides to an existing 3 OH end C. Can't add nucleotides to a chain, but can make covalent bonds D. Actually a specialized form of RNA polymerase select 1. DNA polymerase select 2. Primase select 3. Ligase select v 4. Helicasearrow_forwardWhich of the following statements are TRUE?I. DNA replication is a semiconservative process wherein the two resulting double helices consist of one new strand and one parental strand.II. The DNA strand that is used to make a complementary daughter strand is called the parental strand.III. The precursor of each new nucleotide in the DNA strand is a deoxynucleoside 3′-triphosphate.IV. The incoming nucleotide always attaches to 5′-phosphate of the previously added nucleotide a. I only b. II only c. I and IV d. III and IVarrow_forwardWhich of the following statements are TRUE?I. DNA replication is a semiconservative process wherein the two resulting double helices consist of one new strand and one parental strand.II. The DNA strand that is used to make a complementary daughter strand is called the parental strand.III. The precursor of each new nucleotide in the DNA strand is a deoxynucleoside 3′-triphosphate.IV. The incoming nucleotide always attaches to 5′-phosphate of the previously added nucleotidearrow_forward
- Although prokaryotes and eukaryotes use different versions, what is the general name of the major DNA building enzyme used in replication? Select one: O a. ligase O b. DNA polymerase O c. RNA polymerase O d. primasearrow_forwarda. unwinds the DNA helix b. stabilizes and stops the two strands from annealing (rebinding with each other) c. recoils the DNA d. cleaves both strands of DNA to relieve tension at supercoils e. places RNA primers at their proper location on the template strands f. acts as starting points for DNA polymerase g. adds DNA nucleotides to form new DNA strands h. forms phosphodiester bonds to join Okazaki fragments Esc 1. single-strand binding protein 2. helicase 3. DNA ligase 4. RNA primer 5. gyrase 6. DNA polymerase 53°F Cloudy 3 Q Search $ F5 FRarrow_forwardThe spontaneous loss of amino groups from adenine in DNA results in hypoxanthine, an uncommon base, opposite thymine. What combination of proteins cold repair such damage? a. nuclease, DNA polymerase, DNA ligase b.telomerase, primase, DNA polymerase c. telomerase, helicase, single-stranded binding protein d.DNA ligase, replication for proteins, adenylyl cyclasearrow_forward
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