EBK BIOLOGY
EBK BIOLOGY
11th Edition
ISBN: 8220101459800
Author: Byers
Publisher: PEARSON
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Chapter 13, Problem 2AC
Summary Introduction

To review:

The severity of cystic fibrosis (CF) symptoms in case of different allelic combinations in heterozygotes.

Introduction:

CF is an autosomal recessive genetic disorder which is caused by a defect in the gene coding for the CF transmembrane conductance regulator (CFTR) protein. A defective CFTR protein leads to the body secretions like digestive substances, sweat and mucous becoming thick and blocking the ducts resulting in multiple organ failure and ultimately death.

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AaBbCc X AaBbCc individuals are crossed. What is the probability of their offspring having a genotype AABBCC?
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY