Genetics: A Conceptual Approach
Genetics: A Conceptual Approach
6th Edition
ISBN: 9781319050962
Author: Benjamin A. Pierce
Publisher: W. H. Freeman
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Chapter 12.4, Problem 39CQ
Summary Introduction

To propose: A mechanism through which, protein A and protein B normally regulate replication so that each cell gets the proper amount of DNA.

Introduction:

Normally in eukaryotes, DNA replicated for once in every cell cycle. The process of replication should be regulated to maintain genetic stability. In the given case, protein A is produced by normal cells and present during S phase. Protein B is found during G1 phase of cell cycle and removes from during the removes during the S phase.

Summary Introduction

To explain: The way through which a mutation in genes of protein A and protein B produces the effects of as given in the discussion.

Introduction:

The cells that contain mutated gene that encoding protein A, the protein is non-functional. This leads to an uncontrolled replication throughout the cell cycle. It results fifty times more DNA molecules than normal DNA molecules carried by the cells.  The cells that contain mutated gene of protein B, the protein is non-functional and it fails to be removed and remain high during the cell cycle.

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