Campbell Biology In Focus, Loose-leaf Edition (3rd Edition)
3rd Edition
ISBN: 9780134895727
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky
Publisher: PEARSON
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Textbook Question
Chapter 12, Problem 6TYU
You design Drosophila crosses to provide recombination data for gene a, which is located on the chromosome shown in Figure 12.12. Gene a has recombination frequencies of 14% with the vestigial-wing locus and 26% with the brown-eye locus. Approximately where is gene a located along the chromosome?
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The genetic map was based on crosses in Drosophila involving the three sex-linked genes a, b and c. “a” gives red eyes, “b” gives normal wings and “c” gives black body. The recombination frequencies between these genes are as follows; a and b is 23.8, b and c is 2.6 and a and c is 28.1, respectively. Could you draw a basic genetic map based on distance between these genes using dots to show distance(s)? Could you make one fundamental comment using these distances based on genetic linkage?
In a series of mapping experiments, the recombination frequencies for four different linked genes of the Drosophila fly were determined, as shown in the figure. Based on this information, what is the most probable
order of these genes on the chromosome?
b 0
cn
90
rb
3.5 6.5 0
vg 19 9.0 16 0
b
cn rb vg
The numbers in the boxes are the
recombination frequencies in between the
genes (in percent).
O b-rb-cn-vg
O vg-cn-b-rb
Orb-cn-vg-b
b = black body
cn = cinnabar eyes
rb = reduced bristles
vg = vestigial wings
O vg-b-rb-cn
In Drosophila (fruit flies), pink eyes (P), curled wings (C), a hairy body (H), and an ebony body (E) are determined by genes located on the same chromosome.
Gene Combination
Recombination Frequency
E/H
41.7%
C/H
18.2%
E/P
22%
H/P
19.7%
Which of the following gene maps shows the gene sequence on this chromosome?
Chapter 12 Solutions
Campbell Biology In Focus, Loose-leaf Edition (3rd Edition)
Ch. 12.1 - Which one of Mendels laws relates to the...Ch. 12.1 - MAKE CONNECTIONS Review the description of meiosis...Ch. 12.1 - WHAT IF? Propose a possible reason that the first...Ch. 12.2 - A white-eyed female Drosophila is mated with a...Ch. 12.2 - Neither Tim nor Rhoda has Duchenne muscular...Ch. 12.2 - MAKE CONNECTIONS Consider what you learned about...Ch. 12.3 - When two genes are located on the same chromosome,...Ch. 12.3 - For each type of offspring of the testcross in...Ch. 12.3 - WHAT IF? Genes A, B, and C are located on the same...Ch. 12.4 - About 5% of individuals with Down syndrome have a...
Ch. 12.4 - WHAT IF? The ABO blood type locus has been mapped...Ch. 12.4 - MAKE CONNECTIONS The gene that is activated on the...Ch. 12.4 - Women born with an extra X chromosome (XXX) are...Ch. 12 - A man with hemophilia (a recessive, sex-linked...Ch. 12 - Pseudohypertrophic muscular dystrophy is an...Ch. 12 - A space probe discovers a planet inhabited by...Ch. 12 - Using the information from problem 3, scientists...Ch. 12 - A man with red-green color blindness (a recessive,...Ch. 12 - You design Drosophila crosses to provide...Ch. 12 - A wild-type fruit fly (heterozygous for gray body...Ch. 12 - Assume that genes A and B are 50 map units apart...Ch. 12 - Prob. 9TYUCh. 12 - SCIENTIFIC INQUIRY DRAW IT Assume you are mapping...Ch. 12 - FOCUS ON EVOLUTION Crossing over is thought to be...Ch. 12 - FOCUS ON INFORMATION The continuity of life is...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE Butterflies have an X-Y...
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- You are studying four linked genes located on chromosome 2 in the fruit fly Drosophila melanogaster: adp (which contributes to obesity), b (which contributes to body color), pr (which contributes to metabolism), and vg (which contributes to wing formation). A series of crosses between pair-wise combinations of these mutations yielded the following recombination frequencies between the indicated loci: pr and adp 9% adp and b 6% pr and b 3% vg and b 10% vg and pr 7% What is the genetic distance in map units (cM) between the adp and vg loci? 16 9 6 4arrow_forwardIn a mutant screen in Drosophila, you identified a gene related to memory, as evidenced by the inability of recessive homozygotes to learn to associate a particular scent with the availability of food. Given another line of flies with an autosomal mutation that produces orange eyes, design a series of crosses to determine the map distance between these two loci. You do not need to calculate recombination frequency.arrow_forwardThe genome of Drosophila has been studied extensively using the technique of gene mapping. In Drosophila, pink eyes (P), curled wings (C), hairy body (H), and ebony body (E) are determined by alleles of genes located on the same chromosome. Gene Combination E/H C/H E/P H/P Frequency of Recombination 44% 23% 23% 21% Draw a gene map showing the correct order these genes appear on the chromosome. How frequently are the genes for pink eyes and curled wings expected to separate during crossing over?arrow_forward
- To determine the recombination frequency between body color and wing genes in flies, you perform several crosses where you cross an F1 having red body and smooth wings with a yellow-bodied, crinkle-winged fly. You get the following results. What is the distance between the genes for body color and wing surface in map units?arrow_forwardDrosophila females heterozygous for three recessive mutations, a, b, and c , were crossed to males homozygous for all three mutations.The cross yielded the following results: in the image Q. Construct a linkage map showing the correct order of these genes and estimate the distances between them.arrow_forwardThe genes dumpy wings (dp), clot eyes (cl), and apterous wings (ap) are linked on chromosome II of Drosophila. In a series of two-point mapping crosses, the genetic distances shown below were determined. What is the sequence of the three genes? dp–ap 42 dp–cl 3 ap–cl 39arrow_forward
- Consider a maize plant: Genotype C/cm ; Ac/Ac+ where cm is an unstable colorless allele caused by Ds insertion. What phenotypic ratios would be produced and in what proportions when this plant is crossed with a mutant c/c Ac+/Ac+? Assume that the Ac and c loci are unlinked, that the chromosome-breakage frequency is negligible, and the C allele encodes pigment production.arrow_forwardThe normal sequence of markers on a certain Drosophila chromosome is ABCDE*FGHIJK, where the asterisk represents the centromere. Some flies were isolated with a chromosome aberration that has the following structure: ABCDE*FIJK . This represents a O a) deletion of GH segment O b) inversion of GH segment O c) deletion O d) deletion of centromerearrow_forwardYou are mapping three linked loci in Drosophila melanogaster (the common laboratory fruit fly). You cross flies that are triply mutant for apricot (pale eyes), bristle (extra bristles) and clipped (notched wings) to wild-type flies. The F+ flies are wild-type in appearance. You then backcross the F+ females to pure-breeding (apricot, bristle, clipped) males and score the phenotypes of 1000 F progeny for all three loci. Here are the results: 359 wild-type 361 apricot, bristle, clipped 89 bristle, clipped 91 apricot 42 apricot, bristle 38 clipped 9 apricot, clipped 11 bristle Using these data, first determine what gametes from the F; trihybrid produced each of the eight F2 categories. Note that apricot = aa (recessive to wild-type A); bristle = bb (recessive to wild-type B); and clipped = cc (recessive to wild-type C). Then determine if each gamete is recombinant (R) or nonrecombinant (R) for each pair of alleles (that is, for each genetic interval). Complete the table by dragging the…arrow_forward
- In Drosophila (fruit flies), jammed wings (J), daughterless (da), curly wings (Cy), star eyes (S), and a black body (b) are determined by genes located on the same chromosome. Gene Combination Recombination Frequency J and Cy 34.9 J and da 1.7 S and Cy 4.8 Cy and b 42.4 S and da 38 b and S 47.2 What is the map unit distance between b and da?Answer map unitsRecord your answer as a value rounded to one decimal place.arrow_forwardFemales of wild-type Strain A and males of mutant Strain B, as well as females of mutant Strain B and males of wild-type Strain A, make reciprocal crosses. Explain why reciprocal crosses are needed in genetics experiments involving Drosophila fruit flies.arrow_forwardThe genes dumpy (dp), clot (cl), and apterous (ap) are linked on chromosome II of Drosophila. In a series of two-point mapping crosses, the following genetic distances were determined. What is the sequence of the three genes? dp–ap 42 dp–cl 3 ap–cl 39arrow_forward
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