Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Textbook Question
Chapter 12, Problem 6TYU
What evidence suggests that during anaphase, kinetochore microtubules shorten at the kinetochore?
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At what stage of mitosis can the kind and number of chromosomes be easily detected and determined?
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Mad protein accumulates on the kinetochores that are not attached to mitotic spindle during metaphase. What do you expect when Mad protein accumulation is artificially inhibited?
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increased risk of aneuploid in daughter cells.
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Chapter 12 Solutions
Biological Science (7th Edition)
Ch. 12 - 1. Which statement about the daughter cells...Ch. 12 - After S phase, what comprises a single chromosome?...Ch. 12 - Progression through the cell cycle is regulated by...Ch. 12 - 4. What major events occur during anaphase of...Ch. 12 - 5. Identify at least two events in the cell cycle...Ch. 12 - 6. What evidence suggests that during anaphase,...Ch. 12 - 7. Evaluate each of the following defects. Which...Ch. 12 - Prob. 8TYUCh. 12 - Prob. 9TYPSSCh. 12 - Prob. 10TYPSS
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- In mitosis, what chromatid combination(s) will be present during metaphase? What combination(s) will be present at each pole at the completion of anaphase?arrow_forwardWhat molecular mechanism seems to be responsible for the movement of the poles during anaphase?arrow_forwardIn a Drosophila where somatic cells have 8 chromosomes, and gametes have 4 chromosomes, what is the number of tetrads in a cell during metaphase II?arrow_forward
- illustrate and briefly describe the alignment, pairing, and disjunction ofsister chromatids during mitosis. Include the molecular complexes cohesin and shugoshin and the enzyme separase.arrow_forwardDuring which phases of the mitotic cycle would the terms chromosome and chromatid refer to identical structures?arrow_forwardOverall, meiosis and mitosis are analogous processes involving many of the same proteins. However, some proteins function uniquely in each of these cell-division events. Explain the meiosis-specific function of the following: (a) Ime2, (b) Rec8, (c) monopolin.arrow_forward
- A typical somatic cell from a badger, which is a diploid, sexually reproducing animal, contains a total of 32 chromosomes. Gametogenesis in badgers is similar to humans. What is the genome size for the badger in terms of chromosome number? How many DNA molecules would be found in a secondary oocyte before dividing? How many chromosomes would be found in a cell at metaphase? How many DNA molecules should be in a tetraploid liver cell from the badger?arrow_forwardIn kangaroos, the somatic cells are diploid, having 22 chromosomes. How many chromosomes are present in each cell at metaphase II of meiosis?arrow_forwardWhat are the three types of microtubules involved in the formation of the mitotic spindle? Briefly describe the contribution of each to successful cell division.arrow_forward
- Explain why we can say that M-phase of the cell-cycle is triggered by a positive feedback loop. a) What would the consequences be if cohesins were working normally but condensins were not? and b) what stage of the cell cycle would this cause problems in? Why is it important for the centrosome to duplicate during G1-G2 (interphase) before M phase? The kinetochores serve as a link between the sister chromatids and the microtubules attached to the mitotic spindle. a) How are microtubules still able to exhibit dynamic instability after they are bound to the sister chromatids and b) why is this important to mitosis? As the name suggests, the Anaphase-promoting-complex (APC), promotes the 4th phase of mitosis by separating the sister chromatids so they can travel to separate poles of the cell, and prevents them from being re-zipped together. Describe how APC does these two things (Hint: one involves M-cyclin and the other involves…arrow_forwardAsymmetric cell division often relies on cytoskeletal elements to generate or maintain the asymmetric distribution of cellular factors. In S. cerevisiae, what factor is localized to the bud by myosin motors? In Drosophila neuroblasts, what factors are localized apically by microtubules?arrow_forwardHow many kinetochores would you expect to find in a cell that has 25 pairs of homologous chromsomes undergoing mitosis?arrow_forward
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