Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 12, Problem 3TYK
Progression through the cell cycle is regulated by oscillations in the concentration of which type of molecule?
a. p53, Rb, and other tumor suppressors
b. receptor tyrosine kinases
c. cyclins
d. cyclin-dependent kinases
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Describe the relationship between cell cycle and link to cancer. Use the following terms in your explanation: tumor, oncogene, tumor suppressor, apoptosis.
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Chapter 12 Solutions
Biological Science (7th Edition)
Ch. 12 - 1. Which statement about the daughter cells...Ch. 12 - After S phase, what comprises a single chromosome?...Ch. 12 - Progression through the cell cycle is regulated by...Ch. 12 - 4. What major events occur during anaphase of...Ch. 12 - 5. Identify at least two events in the cell cycle...Ch. 12 - 6. What evidence suggests that during anaphase,...Ch. 12 - 7. Evaluate each of the following defects. Which...Ch. 12 - Prob. 8TYUCh. 12 - Prob. 9TYPSSCh. 12 - Prob. 10TYPSS
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- Which negative regulatory molecule can trigger cell suicide (apoptosis) if vital cell cycle events do not occur? a. p53 b. p21 c. retinoblastoma protein (Rb) d. cyclin-dependent kinase (Cdk)arrow_forwardDescribe how tumor suppressors function to stop the cell cycle until certain events are completedarrow_forwardHow is apoptosis involved in cancer? Describe the role of apoptosis in cancer and identify what molecules are involved. Cite your references. asap.arrow_forward
- Which component of cell division machinery is frequently targeted by anti-cancer drugs? Can you explain the common side-effects of chemotherapy (e.g. hair loss, mucositis) based on this information?arrow_forwardSometimes a cells "deal with" damaged DNA by just killing off the cell. This special cellular suicide is called apoptosis. Usually, the cell cycle has checkpoints that prevent damaged/mutated cells from proceeding to the next phase, though. When these checkpoints don't work, apoptosis can be used. If apoptosis did NOT occur, how might the damaged DNA impact the rest of the cell cycle? A. it may not complete the cell cycle correctly B. new cells containing damaged DNA may be made C. the cell may enter G0 D. all of the above are options E. A and B, but not C F. B and C, but not Aarrow_forwardWhat is the role of executioner proteins in apoptosis?a. They kill the cell by destroying its proteins.b. They function as the “death receptors” on the surface of the cell.c. They are part of the immune response that eliminates the cells.d. They cause the cell to swell and burst.arrow_forward
- Oncologists (cancer doctors) frequently measure the mitotic index of tumor cells when they are removed via surgery or biopsy. What do you think is the value of finding out the mitotic index of these cells?arrow_forwardHow does MPF trigger M phase of the cell cycle? A. MPF phosphorylates proteins that triggers the activation of M phase B. MPF has a regulatory role in breakdown of the nuclear envelope during M phase C. MPF is a dimer subunit that is turned on during S phase to aid with chromosome replication D. MPF Cdk subunits regulate M phasearrow_forwardThe majority of the cells undergo selective activation of the DNA which would lead to cells developing specialized structures and specialized features, a process known as a. differentiation b. apoptosis c. cell division d. cytokinesisarrow_forward
- Which of the following proteins would least likely promote arrest of cell division or apoptosis? Select one: a. p21 b. superoxide c. retinoblastoma d. p53 e. cyclinarrow_forwardDescribe how the tumor-suppressor genes Rb, p53 and p21 regulate the cell cycle.arrow_forwardIdentify which of the following statements is a lie? Select one: a. Apoptosis occurs as the body produces certain enzymes that initiate degradation of nuclear and cytoplasmic material, breaking the cell into necrosis bodies. b. Apoptosis helps maintain a healthy and normal population of cells. c. Apoptosis plays an essential role in growth, immune surveillance, and embryological development.arrow_forward
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