Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 12, Problem 6P
The enzyme micrococcal nuclease can cleave phosphodiester bonds on single- or double-stranded DNAs, but DNA that is bound to proteins is protected from digestion by micrococcal nuclease. When chromatin from eukaryotic cells is treated for a short period of time with micrococcal nuclease and then the DNA is extracted and analyzed by electrophoresis and ethidium bromide staining, the pattern shown in lane A on the following gel is found. Treatment for a longer time results in the pattern shown in lane B, and treatment for yet more time yields that shown in lane C. Interpret these results.
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The metabolic pathway below is used for the production of the purine nucleotides adenosine monophosphate (AMP) and guanosine monophosphate (GMP) in eukaryotic cells. Assume each arrow represents a reaction catalyzed by a different enzyme. Using the principles of feedback inhibition, propose a regulatory scheme for this pathway that ensures an adequate supply of both AMP and GMP, and prevents the buildup of Intermediates A through G when supplies of both AMP and GMP are adequate.
QUESTION 27
Label the structures marked A, B, C and explain the role of structure A.
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Chapter 12 Solutions
Genetics: From Genes to Genomes
Ch. 12 - For each of the terms in the left column, choose...Ch. 12 - Many proteins other than histones are found...Ch. 12 - What difference exists between the compaction of...Ch. 12 - What is the role of the core histones in...Ch. 12 - a. About how many molecules of histone H2A would...Ch. 12 - The enzyme micrococcal nuclease can cleave...Ch. 12 - a. What letters are used to represent the short...Ch. 12 - About 2000 G bands are visible in a...Ch. 12 - Suppose you performed a fluorescence in situ...Ch. 12 - Which of the following would be suggested by a...
Ch. 12 - For each of the following pairs of chromatin...Ch. 12 - a. Drosophila b. Humans Give examples of...Ch. 12 - One histone modification that is seen consistently...Ch. 12 - Recently, scientists constructed a transgene that...Ch. 12 - Drosophila geneticists have isolated many...Ch. 12 - On the following figures, genes A and B are on the...Ch. 12 - Prob. 17PCh. 12 - The first page of this chapter displays photos of...Ch. 12 - The human genome contains about 3 billion base...Ch. 12 - The mitotic cell divisions in the early embryo of...Ch. 12 - In an experiment published in the journal Cell in...Ch. 12 - a. What DNA sequences are found at the telomeres...Ch. 12 - Prob. 23PCh. 12 - a. In a fluorescent in situ hybridization FISH...Ch. 12 - If you are comparing the two telomeres in each...Ch. 12 - a. What DNA sequences are commonly found at human...Ch. 12 - On the graphs presented in Problem 21, no data is...Ch. 12 - Prob. 29PCh. 12 - Prob. 30PCh. 12 - In the 1920s, Barbara McClintock, later a Nobel...Ch. 12 - Give at least one example of a chromosomal...Ch. 12 - Cornelia de Lange syndrome CdLS is a rare human...Ch. 12 - a. Give at least three examples of types of...Ch. 12 - A number of yeast-derived elements were added to...Ch. 12 - Prob. 36PCh. 12 - The completely synthetic yeast chromosome Syn III...
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- Draw a gram negative bacterial cell below. Your cell should have the following parts, labeled: A bacillus shape Fimbriae Amphitrichous flagella 2 membranes (outer and inner) The outer membrane should have lipopolysaccharide (LPS) with lipid A and O antigens Periplasmic space The thin peptidoglycan cell wall between the 2 membranes A nucleoid Ribosomes Inclusionsarrow_forwardBacterial species Cell wall type Example: S. mitis Gram positive S. epidermidis H. pylori M. bovis S. marcescens Shape and arrangement Coccus, streptococcus Drawing 0000000arrow_forwardDraw a gram positive bacterial cell below. Your cell should have the following parts, labeled: A coccus shape A capsule The gram positive cell wall should have the peptidoglycan labeled, as well as its component parts (NAM, NAG, and teichoic acid) A cell membrane Fimbriae A nucleoid Ribosomes Inclusionsarrow_forward
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