HUMAN ANATOMY + PHYSIOLOGY + MAST AP
HUMAN ANATOMY + PHYSIOLOGY + MAST AP
11th Edition
ISBN: 9780136782056
Author: Marieb
Publisher: INTER PEAR
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Chapter 12, Problem 2CCS

39-Year-Old Female with Traumatic Brain Injury

Margaret Bryans, a 39-year-old female, lost control while skiing and hit her head on a tree. She regained consciousness en route to the hospital and appeared agitated and combative. Paramedics observed that she had a right hemiparesis (muscle weakness), with a nearly complete paresis of her right upper extremity and a partial paresis of the right lower extremity. A head CT scan revealed an acute subdural hematoma and an extensive subarachnoid hemorrhage. Doctors noted that she was able to follow commands from medical personnel. However, she could only speak haltingly, using simple words.

Chapter 12, Problem 2CCS, 39-Year-Old Female with Traumatic Brain Injury Margaret Bryans, a 39-year-old female, lost control

Surgery to remove large clots from the subarachnoid space was performed immediately. Two weeks after the surgery, she showed significant improvement in her speech and motor function.

2. Which side of the brain is involved in Mrs. Bryans’s injury? What evidence did you use to determine this?

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.

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