
(a) Interpretation:
The balanced equation for the reaction catalyzed by PFK-2 should be written.
Concept Introduction:
PFK-2 is an enzyme that indirectly regulates the glycolysis rate in the cells. It is known to be a bifunctional enzyme due to its structure. The two domains independently act as functional enzymes because both are located on one protein honodimer.
In mammals, different PFK-2 isoforms are encoded by genetic mechanisms to accommodate tissue specific needs. General function of PFK-2 remains the same. Slight differences in enzymatic properties are featured by isoforms which are then controlled by different methods of regulation.
(b) Interpretation:
The balanced equation for the conversion of 2 moles of oxaloacetate to glucose should be written.
Concept Introduction:
Gluconeogenesis is a
(c) Interpretation:
The balanced equation for the conversion of glucose to UDP-Glc should be written.
Concept Introduction:
ATP to ADP conversion is reduction reaction. Energy released from the hydrolysis of ATP to ADP, this energy is used in cellular processes. Also, ADP can combined with a phosphate to form ATP, the reaction is as follows:
(d) Interpretation:
The balanced equation for the conversion of 2 moles of glycerol to glucose should be written.
Concept Introduction:
ATP to ADP conversion is reduction reaction. Energy released from the hydrolysis of ATP to ADP, this energy is used in cellular processes. Also, ADP can combine with a phosphate to form ATP, the reaction is as follows:
Also, NAD+ is an oxidizing agent as it accepts electrons from other molecules to get reduced to NADH. Here, NADH can act as a reducing agent to donate electrons. Thus, the main function of NAD is electron transfer reaction.
(e) Interpretation:
The balanced equation for the conversion of 2 moles of malate to glucose-6-phosphate should be written.
Concept Introduction:
ATP to ADP conversion is reduction reaction. Energy released from the hydrolysis of ATP to ADP, this energy is used in cellular processes. Also, ADP can combine with a phosphate to form ATP, the reaction is as follows:
Similarly, the conversion of GTP to GDP is also a reduction reaction.

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Chapter 12 Solutions
Biochemistry: Concepts and Connections
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- 3. Which one of the compounds below is the major product formed by the reaction sequence shown here? CH3 + CH3NO2 NaOH H2, Ni ? nitromethane acetophenone OH OH HO HN- u x x x x Ph A HO -NH2 HO H Ph Ph Ph N- H B Ph NH2 D Earrow_forward4. Only ONE of the five compounds below can be prepared by an aldol condensation in which a single carbonyl compound is treated with base. Which one is it? To solve this problem, reverse the aldol condensation that formed each of these molecules to find out what two molecules came together to make the products. The one in which the two molecules are identical is the answer. Ph Ph ཚིག གནས ག ནཱ ཀ ན ཀནཱ A Ph H B Ph Ph H D Ph. Ph Ph E Harrow_forward5. Which one is the major organic product obtained from the following reaction sequence? First, equimolar amounts of cyclopentanone and LDA are mixed at -78°C. Then propionaldehyde (propanal) is added. Addition of aqueous acid completes the process. LDA, -78°C. 1. 2. H₂O* H A B H 0 D H H Earrow_forward
- 2. Which one is the major organic product obtained from the following reaction? NaOH, H₂O heat A B C D Earrow_forwardCH3CH2CHO + propanal PhCH2CHO 2-phenylacetaldehyde mixture of four products NaOH 10. In the crossed aldol reaction of propanal and 2-phenylacetaldehyde shown above, a mixture of four products will be formed. Which ONE of the compounds below will NOT be formed in this crossed aldol reaction? OH Ph A H OH OH Ph H B OH OH H H H Ph Ph C Ph D Earrow_forwardAn organic chemist ordered the wrong item. She wanted to obtain 1-hydroxy-2-butanone, butinstead ordered 2-hydroxybutyraldehyde. As a good biochemist, show how the organic chemistcould use biological catalysis to make her desired compound.arrow_forward
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