Concept explainers
(1)
To determine:
How a microbiologist could determine that the fungal infection in a patient’s lung was ascomycete instead of a basidiomycete. Why aspergillosis is emerging as a new disease. Why a powerful drug like voriconazole is effective against fungi and comparatively harmless to humans.
Case summary:
The patient was not in a good shape. He had nothing to do with his physique or to spend time at the gym but had to do with the ball of
Unfortunately, the disease has not peaked yet for the patient. The fungus Aspergillus invaded his blood and even progressed toward his brain. The symptoms and signs of invasive aspergillosis would be an excessive weakness, extreme tiredness, severe headaches, and delirium which were found to be his daily companion. One side of his body might also be paralyzed.
The patient spent four weeks in the hospital. The brain was being pierced by thin hyphal threads. His personality was almost worsened and he can’t able to get hold of himself. At any time, he would lapse into unconsciousness.
A new antifungal drug (voriconazole) brought the patient back to life. A medical miracle happened with the help of this drug, and the invasive mold was defeated.
(2)
To explain:
Why aspergillosis is emerging as a “new” disease.
Case summary:
The patient was not in a good shape. He had nothing to do with his physique or to spend time at the gym but had to do with the ball of fungus that is present in his right lung. Aspergilloma is a fungal sphere that occurred by the single spore of Aspergillus (an ascomycete fungus). The mold had formed by the fungal hyphae mass that invades his lung airways and killing him slowly. This kind of bronchopulmonary aspergillosis is a rare but frequently increasing pathogen in immunocompromised people. Apart from difficulty in fever, chest pain, and breathing, the patient hated the most was coughing up of bloody mucus. He coughed up his lung pieces out.
Unfortunately, the disease has not peaked yet for the patient. The fungus Aspergillus invaded his blood and even progressed toward his brain. The symptoms and signs of invasive aspergillosis would be an excessive weakness, extreme tiredness, severe headaches, and delirium which were found to be his daily companion. One side of his body might also be paralyzed.
The patient spent four weeks in the hospital. The brain was being pierced by thin hyphal threads. His personality was almost worsened and he can’t able to get hold of himself. At any time, he would lapse into unconsciousness.
A new antifungal drug (voriconazole) brought the patient back to life. A medical miracle happened with the help of this drug, and the invasive mold was defeated.
(3)
To define:
Why voriconazole drug is effective against fungi and harmless to humans.
Case summary:
The patient was not in a good shape. He had nothing to do with his physique or to spend time at the gym but had to do with the ball of fungus that is present in his right lung. Aspergilloma is a fungal sphere that occurred by the single spore of Aspergillus (an ascomycete fungus). The mold had formed by the fungal hyphae mass that invades his lung airways and killing him slowly. This kind of bronchopulmonary aspergillosis is a rare but frequently increasing pathogen in immunocompromised people. Apart from difficulty in fever, chest pain, and breathing, the patient hated the most was coughing up of bloody mucus. He coughed up his lung pieces out.
Unfortunately, the disease has not peaked yet for the patient. The fungus Aspergillus invaded his blood and even progressed toward his brain. The symptoms and signs of invasive aspergillosis would be an excessive weakness, extreme tiredness, severe headaches, and delirium which were found to be his daily companion. One side of his body might also be paralyzed.
The patient spent four weeks in the hospital. The brain was being pierced by thin hyphal threads. His personality was almost worsened and he can’t able to get hold of himself. At any time, he would lapse into unconsciousness.
A new antifungal drug (voriconazole) brought the patient back to life. A medical miracle happened with the help of this drug, and the invasive mold was defeated.
Want to see the full answer?
Check out a sample textbook solutionChapter 12 Solutions
EP MICROBIOLOGY:W/DISEASES BY..-MOD.ACC
- Identify the indicated cavity (Fucus). a. antheridia b. conceptacel c. receptacle d. oogonium e. none of thesearrow_forwardIdentify the indicated structure (Saprolegnia). a. antheridium O b. oospore c.sperm d. auxospore e. tetraspore Of. zygosporearrow_forwardUsing information from the primary literature (several references have been provided as a starting point below) please answer the following question: Based on your review of the literature on rewilding, what are the major scientific pros and cons for rewilding? Please note that the focus of this assignment are the (biological) scientific issues associated with rewilding. As will be discussed in class, there are a number of non-scientific issues involved or implicated in rewilding, all ultimately affecting the public acceptability of rewilding. Although these issues are important – indeed, critical – in this assignment you should focus on the biological science issues and questions. Details: You must enumerate at least two pros and at least two cons. Your answer should be no more than 500 well-chosen words, excluding references. Think carefully about how best to organize and structure your answer. Aim for high information density: say a lot, but say it succinctly. Recall Nietzche’s…arrow_forward
- Using information from the primary literature (several references have been provided as a starting point below) please answer the following question: Based on your review of the literature on rewilding, what are the major scientific pros and cons for rewilding? Please note that the focus of this assignment are the (biological) scientific issues associated with rewilding. As will be discussed in class, there are a number of non-scientific issues involved or implicated in rewilding, all ultimately affecting the public acceptability of rewilding. Although these issues are important – indeed, critical – in this assignment you should focus on the biological science issues and questions. Details: You must enumerate at least two pros and at least two cons. Your answer should be no more than 500 well-chosen words, excluding references. Think carefully about how best to organize and structure your answer. Aim for high information density: say a lot, but say it succinctly. Recall Nietzche’s…arrow_forwardNow draw a rough sketch of what the control data might look like if in addition to the specific binding, there was also a considerable amount of nonspecific binding (again using a normal dose/response curve) (do % total bound ligand vs concentration)arrow_forwardWhat are functions of cuboidal cells in the kidney? Select all that apply. Concentration of gases Dilution of chemicals Secretion of molecules Nutrition to tissues Support of tissues Absorption of moleculesarrow_forward
- question1 In plants, epithelial tissue is only found as the outermost cell layer and acts as a barrier. In humans, epithelial tissue is found inside the body as well as on the surface. What function(s) does/do epithelial tissue carry out in humans? Select all that apply. Waste storage Filtration Oxygen transport Protection Diffusion Osmosis Absorptionarrow_forwardWhat words best describes this organism? a. Unicellular/nonmotile Ob. unicellular/motile c. colonial/nonmotile d. colonial/motile e. multicelluar O f. siphonous g. none of thesearrow_forwardIdentify the phylum or class. a. Euglenophyta b. Dinoflagellata c. Bacillariophyceae d. Oomycetes e. Phaeophyceae O f. Myxomycota g. Xanthophyceae ○ h. Chrysophyceae i. Dictyosteliomycota O j. Rhodophyta Ok. Chlorophyceaens I. Charophyceaensarrow_forward
- Medical Terminology for Health Professions, Spira...Health & NutritionISBN:9781305634350Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. SchroederPublisher:Cengage LearningMicrobiology for Surgical Technologists (MindTap ...BiologyISBN:9781111306663Author:Margaret Rodriguez, Paul PricePublisher:Cengage Learning
- Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxLifetime Physical Fitness & WellnessHealth & NutritionISBN:9781337677509Author:HOEGERPublisher:Cengage