ANATOMY AND PHYSIOLOGY
17th Edition
ISBN: 9781630180928
Author: OpenStax
Publisher: OPENSTAX C
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Textbook Question
Chapter 12, Problem 16RQ
Which of the following substances is least able to cross the blood-brain barrier?
- water
- sodium ions
- glucose
- white blood cells
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Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly
The pKa values for the peptide's side chains, terminal amino groups, and carboxyl groups are provided in the table.
Amino acid Amino pKa Carboxyl pKa Side-chain pKa
glutamate
9.60
2.34
histidine
9.17
1.82
4.25
6.00
tryptophan
9.39
2.38
serine
9.15
2.21
glycine
9.60
2.34
leucine
9.60
2.36
arginine
9.04
2.17
12.48
proline
10.96
1.99
Calculate the net charge of the molecule at pH 3.
net charge at pH 3:
Calculate the net charge of the molecule at pH 8.
net charge at pH 8:
Calculate the net charge of the molecule at pH 11.
net charge at pH 11:
Estimate the isoelectric point (pl) for this peptide.
pl:
Biology Question
This entire structure (Pinus pollen cone) using lifecycle terminology is called what?
Chapter 12 Solutions
ANATOMY AND PHYSIOLOGY
Ch. 12 - In 2003, the Nobel Prize in Physiology or Medicine...Ch. 12 - Visit this site...Ch. 12 - Visit this site...Ch. 12 - View the University of Michigan Webscope...Ch. 12 - What happens across the membrane of an...Ch. 12 - Visit this site...Ch. 12 - Watch this video...Ch. 12 - Watch this video...Ch. 12 - Which of the following cavities contains a...Ch. 12 - Which structure predominates in the white matter...
Ch. 12 - Which part of a neuron transmits an electrical...Ch. 12 - Which term describes a bundle of axons in the...Ch. 12 - Which functional division of the nervous system...Ch. 12 - What type of glial cell provides myelin for the...Ch. 12 - Which part of a neuron contains the nucleus?...Ch. 12 - Which of the following substances is least able to...Ch. 12 - What type of glial cell is the resident macrophage...Ch. 12 - What two types of macromolecules are the main...Ch. 12 - If a thermoreceptor is sensitive to temperature...Ch. 12 - Which of these locations is where the greatest...Ch. 12 - How long does all the signaling through the...Ch. 12 - What is the target of an upper motor neuron?...Ch. 12 - What ion enters a neuron causing depolarization of...Ch. 12 - Voltage-gated Na+ channels open upon leaching what...Ch. 12 - What does a ligand-gated channel require in order...Ch. 12 - What does a mechanically gated channel respond to?...Ch. 12 - Which of the following voltages would most likely...Ch. 12 - Which of the following is probably going to...Ch. 12 - How much of a change in the membrane potential is...Ch. 12 - A channel opens on a postsynaptic membrane that...Ch. 12 - What neurotransmitter is released at the...Ch. 12 - What type of receptor requires an effector protein...Ch. 12 - Which of the following neurotransmitters is...Ch. 12 - What responses are generated by the nervous system...Ch. 12 - When eating food, what anatomical and functional...Ch. 12 - Multiple sclerosis is a demyelinating disease...Ch. 12 - Which type of neuron, based on its shape, is best...Ch. 12 - Sensory fibers, or pathways, are referred to as...Ch. 12 - If a person has a motor disorder and cannot move...Ch. 12 - What does it mean for an action potential to be an...Ch. 12 - The conscious perception of pain is often delayed...Ch. 12 - If a postsynaptic cell has synapses from five...Ch. 12 - Why is the receptor the important element...
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