The structure of the compound has to be drawn, and Z or E stereochemistry has to be assigned to the product which is underwent E 2 reaction with NaOH. Concept introduction: Z or E stereochemistry: The two similar groups (or higher priority groups) are in same side in double bond of alkenes is called as Z-isomer (or cis isomer). Two similar groups (or higher priority groups) are opposite side in double bond of alkenes is called as E -isomer (or trans isomer). Example: E 2 elimination: Alkyl halide forms an alkene from the abstraction of the proton from the β-carbon atom followed by elimination of the bromine in a single step. Given information: The molecule is given in Ball-and-stick model and it undergoes E 2 elimination with NaOH.

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Recent advancements in liquid chromatography include the development of ultrahigh pressure liquid chromatography (UHPLC) and an increased use of capillary columns that had previously only been used with gas chromatography. Both of these advances have made the development of portable LC systems possible. For example, Axcend Corp. makes a portable system that uses a capillary column with an internal diameter of 150-μm-that is packed with 1.7-um stationary phase particles. In contrast, a traditional LC column has a 4.6 mm internal diameter and utilizes 5-um stationary phase particles. a) Explain one advantage that is afforded by the use of a capillary column in liquid chromatographic separation. Explain one disadvantage of capillary columns. b) Explain how the use of smaller stationary phase particles can improve the resolution of a separation. Include any relevant equations that support your explanation. c) A scientist at Rowan University is using the Axcend LC to conduct analyses of F…

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Question

Chapter 11.SE, Problem 24VC

Interpretation Introduction

Interpretation:

The structure of the compound has to be drawn, and Z or E stereochemistry has to be assigned to the product which is underwent E₂ reaction with NaOH.

Concept introduction:

Z or E stereochemistry:

The two similar groups (or higher priority groups) are in same side in double bond of alkenes is called as Z-isomer (or cis isomer). Two similar groups (or higher priority groups) are opposite side in double bond of alkenes is called as E-isomer (or trans isomer).

Example:

E₂ elimination:

Alkyl halide forms an alkene from the abstraction of the proton from the β-carbon atom followed by elimination of the bromine in a single step.

Given information:

The molecule is given in Ball-and-stick model and it undergoes E₂ elimination with NaOH.

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