Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
10th Edition
ISBN: 9780133922851
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Textbook Question
Chapter 11.3, Problem 4CC
WHAT IF? → If you exposed a cell to a ligand that binds to a receptor and activates phospholipase C, predict the effect the IP3-gated calcium Channel would have on Ca2+ concentration in the cytosol.
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Cleavage
Ligand
Precursor
Receptor
Inactive
Receptor
Active
Cell Membrane
6. The figure above shows a model of a ligand precursor being cleaved to produce an active
ligand that binds to a specific receptor. Which of the following is most likely to reduce the
binding of the active ligand to its receptor?
(A) A change in the cytoskeletal attachment of transmembrane proteins
(B) The presence of a large amount of the precursor form of the ligand
(C) An increase in the ratio of the number of unsaturated to the number of saturated
fatty acid tails of the membrane lipids
(D) A mutation in the receptor gene that causes a substitution of a charged amino acid for a
nonpolar amino acid in the ligand binding site of the receptor
Q-Slide #6
Add icons to show what CaMKII does to its substrate proteins
Ме
СР2
Ca**
CP2
Me
Glu
СВР
HAT
NMDA-R*
CREB
Ca**
Ca*
Ca
CAMKII*
CAMKII
?
The state of the cell shortly after
glutamic acid bound its receptor
Chapter 11 Solutions
Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
Ch. 11.1 - Explain how signaling is involved in ensuring that...Ch. 11.1 - In liver cells, glycogen Phosphorylase acts in...Ch. 11.1 - Prob. 3CCCh. 11.2 - Nerve growth factor (NGF) is a water-soluble...Ch. 11.2 - WHAT IF? What would the effect be if a cell made...Ch. 11.2 - MAKE CONNECTIONS How is ligand binding similar to...Ch. 11.2 - Prob. 4CCCh. 11.3 - What is a protein kinase, and what is its role in...Ch. 11.3 - When a signal transduction pathway involves a...Ch. 11.3 - What is the actual signal that is being transduced...
Ch. 11.3 - WHAT IF? If you exposed a cell to a ligand that...Ch. 11.4 - How can a targct cell's response to a single...Ch. 11.4 - WHAT IF? If two cells have different scaffolding...Ch. 11.4 - Prob. 3CCCh. 11.5 - Give an example of apoptosis during embryonic...Ch. 11.5 - WH AT IF? If apoptosis occurred when it should...Ch. 11 - What determines whether a cell responds to a...Ch. 11 - How are the structures of a GPCR and an RTK...Ch. 11 - What is the difference between a protein kinase...Ch. 11 - What mechanisms in the cell terminale its response...Ch. 11 - What is an explanation for the similarities...Ch. 11 - Binding of a signaling molecule to which type of...Ch. 11 - The activation of receptor tyrosinc kinases is...Ch. 11 - Lipid-soluble signaling molecules, such as...Ch. 11 - Consider this pathway: epinephrine G...Ch. 11 - Apoptosis involves all but which of the following?...Ch. 11 - Which Observation suggestcd to Sutherland the...Ch. 11 - Protein phosphorylation is commonly involved with...Ch. 11 - DRAW IT Draw the following apoptotic pathway,...Ch. 11 - EVOLUTION CONNECTION Identify the evolutlonary...Ch. 11 - Prob. 10TYUCh. 11 - SCIENCE, TECHNOLOGY, AND SOCIETY The aging process...Ch. 11 - WRITE ABOUT A THEME: ORGANIZATION The properties...Ch. 11 - SYNTHESIZE YOUR KNOWLEDGE There are five basic...
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