EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
7th Edition
ISBN: 9780133983401
Author: Silverthorn
Publisher: YUZU
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Chapter 11, Problem 7CC

(a)

Summary Introduction

To determine: The enzyme that converts ATP to cAMP.

Introduction: Enzymes are catalysts which speed up a reaction process by lowering the activation energy of the reactants. They perform the role of aiding in digestion, metabolism, and breaking large molecules into simpler molecules for better absorption.

(b)

Summary Introduction

To determine: The enzyme activated by cAMP.

Introduction: The enzyme adenylyl cyclase is involved in the conversion of ATP into cAMP. ATP stands for “adenosine triphosphate” while cAMP stands for “cyclic adenosine monophosphate.” Some enzymes and proteins need cAMP for their activity.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
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