Concept explainers
(a)
Interpretation:
The reason for the measurement of aggrecan degradation by the release of glycosaminoglycan needs to be explained.
Concept introduction:
The carbohydrates are combined with the proteins. Enzyme behaves aggrecan and produces a molecule.Some destruction can observe by the aggrecan.
(b)
Interpretation:
The reason for the glycosaminoglycan release to not indicate the aggrecan degradation needs to be explained.
Concept introduction:
Glycosaminoglycan is also known as mucopolysaccharides which have a series of disaccharides. This series contains amino sugar and uronic sugar. Glycosaminoglycan is also written as GAGs.
(c)
Interpretation:
The purpose of the control needs to be explained.
Concept introduction:
Enzyme behaves aggrecan and producesa molecule. Some destruction can observe by the aggrecan.
(d)
Interpretation:
The effect of adding IL-2 needs to be explained.
Concept introduction:
IL-2 is also known as interleukin which is a signaling molecule of the immune system.
(e)
Interpretation:
The response of aggrecanase inhibitor when IL-2 is added needs to be explained.
Concept introduction:
IL-2 is also known as interleukin which is a signaling molecule of the immune system.
(f)
Interpretation:
The reason for aggrecan destruction in the control needs to be explained.
Concept introduction:
Enzyme behaves aggrecan and produces a molecule. Some destruction can observe by the aggrecan.
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Chapter 11 Solutions
BIOCHEMISTRY 2 TERM ACCESS
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- For the Oxaloacetate -> Malate reaction, assume the normal ratio of NAD/NADH, what is the maximum ratio of Malate/Oxaloacetate that will allow reaction progress?arrow_forwardA particular particle is trying to cross a membrane by simple diffusion from a high concentration of 20mM to a low concentration of 20uM. If a membrane is 15uM in width, and the diffusion coefficient of the particle is 5 uM/sec, what is the influx in uM/sec?arrow_forwardMechanisms: 1. Give a full arrow-pushing mechanism for the hydrolysis of the gamma phosphate of ATP by an ATPase. 2. Give a full arrow pushing mechanism of the spontaneous redox reaction between NAD+/NADH and oxaloacetate/malate.arrow_forward
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