(a)
Interpretation:
The name of the protein affected by the disease, sickle cell anemia is to be stated.
Concept Introduction:
The genetic material of a living thing which contains DNA and RNA is known as genome. It consists of genes, non-coding DNA and the mitochondrial DNA. The human genome consists of a genome possessed by Homo sapiens that is composed of
(b)
Interpretation:
The name of the protein affected by the disease, Tay Sachs is to be stated.
Concept Introduction:
The genetic material of a living thing which contains DNA and RNA is known as genome. It consists of genes, non-coding DNA and the mitochondrial DNA. The human genome consists of a genome possessed by Homo sapiens that is composed of
(c)
Interpretation:
The name of the protein affected by the disease, Leprechaunism is to be stated.
Concept Introduction:
The genetic material of a living thing which contains DNA and RNA is known as genome. It consists of genes, non-coding DNA and the mitochondrial DNA. The human genome consists of a genome possessed by Homo sapiens that is composed of
(d)
Interpretation:
The name of the protein affected by the disease, Hartnup disorder is to be stated.
Concept Introduction:
The genetic material of a living thing which contains DNA and RNA is known as genome. It consists of genes, non-coding DNA and the mitochondrial DNA. The human genome consists of a genome possessed by Homo sapiens that is composed of
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Biochemistry
- Answers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book. CRISPR/Cas9: Design of a gRNA to Target the Human PVALB Gene The human PVALB gene, which encodes the Ca2+-binding protein parvalbumin, can be Targeted by CRISPR/Cas9, at the protospacer sequence - ATGCAGGAGGGTGGCGAGAGGGGCCGAGAT- followed by a -TGG-PAM trinucleotide. Give the sequence of the spacer region of a gRNA that will target the complementary DNA strand at this site. Include at the 3'-end of your gRNA sequence a region that will form a stem-loop structure with a 5'-AGCAUAGCUGUAAAAC- sequence downstream in the gRNA to create the dsRNA-binding site for Cas9.arrow_forwardAnswers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book. Abundance of the Different Bases in the Human Genome Results on the human genome published in Science (Science 291 :1304—1350 [2001]) indicate that the haploid human genome consists of 2.91 gigabase pairs (2.91 X ]09 base pairs} and that 27% of the bases in human DNA are A. Calculate the number of A. T, G, and C residues in a typical human cell.arrow_forwardAnswers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book. Cells as Steady-State Systems Describe what is meant by the phrase "cells tire steady-state systems." (Section 1.4)arrow_forward
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- Answers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book. Assessing the Effect of Temperature on Equilibrium You are studying the various components of the venom of a poisonous lizard. One of the venom components is a protein that appears to be temperature sensitive. When heated, it denatures and is no longer toxic. The process can be described by the following simple equation: There is only enough protein from this venom to carry out two equilibrium measurements. At 298 K, you find that 98% of the protein is in its to.\ic form. However, when you raise the temperature to 320 �.. you find that only 10% of the protein is in its toxic form. Calculate the equilibrium constants for the T to N conversion at these two temperatures. Use the data to determine the H,S, and G for this process.arrow_forwardAnswers to all problems are at the end οΓthis book. Detailed solutions are available in the Student Solutions Manual. Study Guide, and Problems Book. Enzymes and Y in the figure are both protein-digesting enzymes found in humans. Where would they most likely be at work? X is found in the mouth, Y in the small intestine. X in the small intestine. Y in the mouth. X in the stomach. Y in the small intestine. X in the small intestine. Y in the stomach.arrow_forwardAnswers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book. Evaluating Nutritional Benefits of Foods In a departure from his usual and highly popular westerns, author Louis L'Amour wrote a novel in 1987, Last of the Breed (Bantam Press), in which a military pilot of Native American ancestry is shot down over the former Soviet Union and is formed to use the survival skills of his ancestral culture to escape his enemies On the rare occasions when he is able to trap and kill an animal for food, he selectively eats the fat, not the meal. Based on your reading of this chapter, what is his reasoning for doing so?arrow_forward
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