Microbiology with Diseases by Body System & Modified MasteringMicrobiology with Pearson eText -- ValuePack Access Card -- for Microbiology with Diseases by Body System Package
1st Edition
ISBN: 9780133857122
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 10, Problem 9MC
Summary Introduction
Introduction:
Viral infections are treated by antiviral drugs rather than the antimicrobial drugs. Maximum antivirals are applied for particular infections of viruses. A wide variety of viruses are treated with the broad-spectrum antiviral agent.
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Chapter 10 Solutions
Microbiology with Diseases by Body System & Modified MasteringMicrobiology with Pearson eText -- ValuePack Access Card -- for Microbiology with Diseases by Body System Package
Ch. 10 - Prob. 1TMWCh. 10 - Some antimicrobial drugs are harmful to humans....Ch. 10 - Antibiotic Overkill A young woman was taking...Ch. 10 - Prob. 3TMWCh. 10 - Why is it incorrect to say that an individual...Ch. 10 - Prob. 1EDCSCh. 10 - Prob. 2CCSCh. 10 - Prob. 1MCCh. 10 - In a Kirby-Bauer susceptibility test, the presence...Ch. 10 - Prob. 3MC
Ch. 10 - Prob. 4MCCh. 10 - Cross resistance is _____. a. the deactivation of...Ch. 10 - Prob. 6MCCh. 10 - Prob. 7MCCh. 10 - Prob. 8MCCh. 10 - Prob. 9MCCh. 10 - Prob. 10MCCh. 10 - Label each figure below to indicate the class of...Ch. 10 - What specific test for antimicrobial efficacy is...Ch. 10 - What characteristics would an ideal...Ch. 10 - Prob. 2SACh. 10 - Why is the fact that drug Z destroys the NAM...Ch. 10 - Given that both human cells and pathogens...Ch. 10 - Prob. 5SACh. 10 - Prob. 6SACh. 10 - Prob. 7SACh. 10 - Prob. 8SACh. 10 - Compare and contrast the actions of polyenes,...Ch. 10 - Prob. 10SACh. 10 - Prob. 1CTCh. 10 - How does Penicillium escape the effects of the...Ch. 10 - How might a colony of Bacillus licheniformis...Ch. 10 - Fewer than 1 % of known antibiotics have any...Ch. 10 - In an issue of News of the Lepidopterists Society,...Ch. 10 - Even though aminoglycosides such as gentamicin can...Ch. 10 - Prob. 7CTCh. 10 - Prob. 8CTCh. 10 - Why might amphotericin B affect the kidneys more...Ch. 10 - Antiparasitic drugs in the benzimidazole family...Ch. 10 - Prob. 11CTCh. 10 - Scientists have cultured bacteria isolated from...Ch. 10 - Prob. 13CTCh. 10 - Prob. 14CTCh. 10 - Enterococcus faecium is frequently resistant to...Ch. 10 - Prob. 1CM
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- Which of the following effects do antiviral drugs not have?a. destroying extracellular virusesb. stopping virus synthesisc. inhibiting virus maturationd. blocking virus receptorsarrow_forwardTo infect their specific host cells, viruses go through these chronological steps EXCEPT a. Release of progeny viruses b. Absorption and penetration of the viral particles c. Uncoating of the nucleic acid of the viral particles d. Synthesis and assembly of viral particle componentsarrow_forwardYou have been hired by a major pharmaceutical company to develop a new vaccine toprevent COVID-19 infection and spread.a. What is a virus? Describe the viral life cycle. (3 marks)b. Describe the difference between an antiviral drug and a vaccine. (1 mark)c. What are three qualities you would prioritize when developing this new vaccine forCOVID-19 that you would want in the end-product? (6 marks) Note: Qualities should be overarching characteristics of the developed drug, not specifics regarding various molecular mechanisms of actionarrow_forward
- An antimicrobial drug binds to the HIV reverse transcriptase enzyme, preventing it from working. Which of the following is true of this drug? It would inhibit early replication steps of some viruses, but not affect normal eukaryotic cell activity. It would directly interfere with translation of some viral proteins and some eukaryotic proteins. It would block assembly/maturation steps of some viruses, and interfere with translation in eukaryotic cells. It would interfere with release of newly formed viruses from a host cell, but not affect eukaryotic cells. It would interfere with protein synthesis in bacteria, but not affect eukaryotic ribosomes. It would interfere with mRNA transcription in bacteria and viruses, but not affect eukaryotic transcription.arrow_forwardConsider the separate stages of an animal virus life cycle. Assemble a short list of structures and processes that are unique to the virus and would make good drug targets for an antiviral agent. Explain your rationale for each choice.arrow_forwardWhich of the following statements are correct for RNA viruses? Mark all that apply. A.Replication requires reverse transcriptase B. Uncoating must occur for the virus to be replicated C.The genome consists of two identical strands of ssRNA D.Replication requires RNA dependent RNA polymerase E. The viral DNA acts as a template for production of viral proteins F.Protease enzyme is required for biosynthesis and maturation of virions G. A provirus stage occurs during viral replicationarrow_forward
- a. Which type of viruses can be directly used for translation? a) dsRNA b) Positive ssRNA c) Retroviruses d) Negative ssRNA b. An antiviral drug specifically modifies viral receptors on a eukaryotic host cell. How might this affect the viral reproductive cycle? It would enhance the process of viral apoptosis It would result in the degeneration of the viral capsid It would facilitate the process of viral endocytosis It would prevent the virus from attaching to the host cellarrow_forwardDetection of active viruses in a lab setting depends on: A. Counting virus protein capsids B. Incubation in medium that promotes the virus metabolism C. Prevention of plaque forming units D. Lysis of an infected cellarrow_forwardWhich of the following statements are correct for retroviruses? Mark all that apply. A. Replication requires reverse transcriptase B.The viral genome acts as a template for production of viral proteins C.The genome consists of two identical strands of ssRNA D. Uncoating must occur for the virus to be replicated E. A provirus stage occurs during viral replication F. The genome consists of dsRNA Protease enzyme is required for biosynthesis and maturation of virions H. Replication requires RNA dependent RNA polymerasearrow_forward
- Which of the following statements are correct for DNA viruses? Mark all that apply. A.The genome consists of dsRNA B. A provirus stage occurs during viral replication C. The genome consists of two identical strands of DNA D. Replication requires reverse transcriptase Replication requires DNA polymerase E.The viral DNA must enter the nucleus for its replication F. Uncoating must occur for the virus to be replicated G.The viral genome acts as a template for production of viral proteinsarrow_forwardWhich of the following events occurs in the lytic cycle of bacteriophage T4 infection but NOT in the lysogenic cycle? a.both digestion of host DNA and viral proteins synthesis b.attachment c.viral protein synthesis d.digestion of host DNA e.entryarrow_forwardIntroduction: There’s quite a bit of interest around repurposing extant drugs to treat infections by targeting host pathways that pathogens rely on. Here are a few potential drugs: 1) A drug that inhibits endocytosis, but not phagocytosis. 2) A drug that inhibits degradation of cytoplasmic proteins into smaller peptides, preventing their cycling back into amino acids. 3) A drug used to treat porphyria that reduces the reactivity of heme. 4) A drug that depletes glutathione, a chemical which protects red blood cells against the reactivity of heme. 5) A drug that reduces expression of the ACE-2 protein. Question: Pick a drug and an infection that the drug is likely to be good at treating, or pick an infection and a drug that would most likely make the infection substantially worse. Which drug and pathogen did you pick? Do you think it’ll make it better or worse?arrow_forward
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