Anatomy and Physiology by OpenStax
17th Edition
ISBN: 9781506698021
Author: J. Gordon Betts;Dean H. Kruse;Kelly A. Young;Peter DeSaix;Brandon Poe;Oksana Korol;James A. Wise;Eddie Johnson;Jody E. Johnson;Mark Womble
Publisher: XANEDU PUBLISHING
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Chapter 10, Problem 45CTQ
How are cardiac muscle cells similar to and different from skeletal muscle cells?
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 10 Solutions
Anatomy and Physiology by OpenStax
Ch. 10 - Watch this video...Ch. 10 - Every skeletal muscle fiber is supplied by a motor...Ch. 10 - The release of calcium ions initiates muscle...Ch. 10 - Muscle that has a striped appearance is described...Ch. 10 - Which element is important in directly Triggering...Ch. 10 - Which of the following properties is not common to...Ch. 10 - The correct order for the smallest to the largest...Ch. 10 - Depolarization of the sarcolemma means ________....Ch. 10 - In relaxed muscle, the myosin-binding site on...Ch. 10 - According to the sliding filament model, binding...
Ch. 10 - The cell membrane of a muscle fiber is called...Ch. 10 - Muscle relaxation occurs when ________. calcium...Ch. 10 - During muscle contraction, the cross-bridge...Ch. 10 - Thin and thick filaments are organized into...Ch. 10 - During which phase of a twitch in a muscle fiber...Ch. 10 - Muscle fatigue is caused by ________. buildup of...Ch. 10 - A sprinter would experience muscle fatigue sooner...Ch. 10 - What aspect of creatine phosphate allows it to...Ch. 10 - Dmg X blocks ATP regeneration from ADP and...Ch. 10 - The muscles of a professional sprinter are most...Ch. 10 - The muscles of a professional marathon runner are...Ch. 10 - Which of the following statements is true? Fast...Ch. 10 - Which of the following statements is false? Slow...Ch. 10 - Cardiac muscles differ from skeletal muscles in...Ch. 10 - If cardiac muscle cells were prevented from...Ch. 10 - Smooth muscles differ from skeletal and cardiac...Ch. 10 - Which of the following statements describes smooth...Ch. 10 - From which embryonic cell type does muscle tissue...Ch. 10 - Which cell type helps to repair injured muscle...Ch. 10 - Why is elasticity an important quality of muscle...Ch. 10 - What would happen to skeletal muscle if the...Ch. 10 - Describe how tendons facilitate body movement.Ch. 10 - What are the five primary functions of skeletal...Ch. 10 - What are the opposite roles of voltage-gated...Ch. 10 - How would muscle contractions be affected if...Ch. 10 - What causes the striated appearance of skeletal...Ch. 10 - How would muscle contractions be affected if ATP...Ch. 10 - Why does a motor unit of the eye have few muscle...Ch. 10 - What factors contribute to the amount of tension...Ch. 10 - Why do muscle cells use creatine phosphate instead...Ch. 10 - Is aerobic respiration more or less efficient than...Ch. 10 - What changes occur at the cellular level in...Ch. 10 - What changes occur at the cellular level in...Ch. 10 - What would be the drawback of cardiac contractions...Ch. 10 - How are cardiac muscle cells similar to and...Ch. 10 - Why can smooth muscles conn act over a wider range...Ch. 10 - Describe the differences between single-unit...Ch. 10 - Why is muscle that has sustained significant...Ch. 10 - Which muscle type(s) (skeletal, smooth, or...
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