BIOLOGY 2E
2nd Edition
ISBN: 9781506699851
Author: OpenStax
Publisher: XANEDU PUBLISHING
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Textbook Question
Chapter 10, Problem 37CTQ
Compare and contrast the roles of the positive cell-cycle regulators negative regulators.
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Chapter 10 Solutions
BIOLOGY 2E
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
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- Diagram and describe the four types of regulatory mechanisms of the cyclin-dependent kinases (Cdks)arrow_forwardWhat are the most important steps in cell-cycle regulation? Give some explanations and present some factors leading to uncontrolled cell cycle.arrow_forwardChanges in the activity of a variety of Cdks are essential for accurate progression through the cell cycle, and yet the levels of Cdk expression are fairly constant during the cell cycle. Briefly describe three mechanisms by which the activity of Cdks is regulated.arrow_forward
- Describe the effects of the mutation causing the p21 promoter to no longer bind p53 on cell signaling pathways and metabolism or cell cycle control.arrow_forwardAfter DNA damage (e.g. caused by X-ray exposure) in eukaryotic cells, the cell cycle can be arrested by the stabilisation of the protein which drives the transcription of the gene, whose protein product interacts with the G1/S-Cdk and S-Cdk complexes. O PDGF, acetyltransferase O phenylalanine hydraxylase, PDGF O p53, acetyltransferase O p53, p21 O p21. p53arrow_forwardModify the diagram above to illustrate specific protein(s) that would participate in regulating this pathway if DNA damage was detected in these cells. What effect would this have on the progression of the cell cycle? If there is more than one possible outcome be sure to outline each one.arrow_forward
- Describe how cyclins and cyclin-dependent kinases are related. How do these molecules help regulate the cell cycle?arrow_forwardDiscuss about Surveillance Mechanisms in Cell Cycle Regulationarrow_forwardIdentify and list the functions of the three general classes of proteins that control cell death.arrow_forward
- Describe what happens to the G1 cell cycle check point of a skin cell that is stimulated to divide by neighboring cells following an injury. Describe the pathway from the growth factor signal to the cell cycle checkpoint regulation of gene expression resulting in cell duplication. Briefly explaining the mechanismarrow_forwardThe expression patterns as well as activation of different types of CDKs happen at different stages of the cell cycle. Explain why.arrow_forwardWhich of the following statements is a lie? Select one: a. The p21 is a multi-functional protein that regulates cell growth and monitors DNA damage on the cells undergoing the preparatory processes during G1. b. Cyclins and Cyclin-dependent kinases (Cdk) need to be tightly bound with each other to regulate the cell cycle by phosphorylating and activating other proteins to advance the cell to the next phase. c. The negative regulators halt the cell cycle and these include Retinoblastoma protein (Rb), p53, and p21.arrow_forward
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