General, Organic, and Biological Chemistry (3rd Edition)
3rd Edition
ISBN: 9780134042428
Author: Laura D. Frost, S. Todd Deal
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 1, Problem 1.114CP
Summary Introduction
To determine:
If dose received by the child is in a safe range.
Introduction:
The amount of dose in a day is calculated by the formula,
Amount of medicine per day=Amount of Drug dose(mg/kg)×Number of dose
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
(a
4 shows scanning electron microscope (SEM) images of extruded
actions of packing bed for two capillary columns of different diameters,
al 750 (bottom image) and b) 30-μm-i.d. Both columns are packed with the
same stationary phase, spherical particles with 1-um diameter.
A) When the columns were prepared, the figure shows that the column with
the larger diameter has more packing irregularities. Explain this observation.
B) Predict what affect this should have on band broadening and discuss your
prediction using the van Deemter terms.
C) Does this figure support your explanations in application question 33?
Explain why or why not and make any changes in your answers in light of
this figure.
Figure 4 SEM images of
sections of packed columns
for a) 750 and b) 30-um-i.d.
capillary columns.³
fcrip
= ↓ bandwidth Il temp
32. What impact (increase, decrease, or no change) does each of the following conditions have on the individual
components of the van Deemter equation and consequently, band broadening?
Increase temperature
Longer column
Using a gas mobile phase
instead of liquid
Smaller particle stationary phase
Multiple Paths
Diffusion
Mass Transfer
34. Figure 3 shows Van Deemter plots for a solute molecule using different column inner diameters (i.d.).
A) Predict whether decreasing the column inner diameters increase or decrease bandwidth.
B) Predict which van Deemter equation coefficient (A, B, or C) has the greatest effect on increasing or
decreasing bandwidth as a function of i.d. and justify your answer.
Figure 3 Van Deemter plots for hydroquinone using different column inner diameters (i.d. in μm). The data was
obtained from liquid chromatography experiments using fused-silica capillary columns packed with 1.0-μm particles.
35
20
H(um)
큰 20
15
90
0+
1500
100
75
550
01
02
594
05
μ(cm/sec)
30
15
10
Chapter 1 Solutions
General, Organic, and Biological Chemistry (3rd Edition)
Ch. 1 - Classify each of the following mixtures as...Ch. 1 - Classify each of the following mixtures as...Ch. 1 - Classify each of the following substances as a...Ch. 1 - Classify each of file following substances as a...Ch. 1 - Classify each of die following as an element or...Ch. 1 - Classify each of the following as an element or a...Ch. 1 - Use the periodic table to supply the missing...Ch. 1 - Use the periodic table to supply the missing...Ch. 1 - Identify and give the number of each element in...Ch. 1 - Identify and give the number of each element in...
Ch. 1 - Give the number of significant figures in each of...Ch. 1 - Give die number of significant figures in each of...Ch. 1 - Complete each of the following calculations and...Ch. 1 - Complete each of the following calculations and...Ch. 1 - A typical aspirin tablet contains 325 mg of the...Ch. 1 - On average, an adults lung volume is 5 L. Convert...Ch. 1 - Prob. 1.17PPCh. 1 - Write scientific notation for the following...Ch. 1 - Express the following numbers in a decimal form:...Ch. 1 - Express the following numbers in a decimal form:...Ch. 1 - Express the following numbers as a percent. Report...Ch. 1 - Express the following numbers as a percent. Report...Ch. 1 - Express the following numbers m decimal form: a....Ch. 1 - Express the following numbers as a fraction: a....Ch. 1 - Prob. 1.25PPCh. 1 - Determine the percent from two numbers given here...Ch. 1 - Based on your experience, is each of the following...Ch. 1 - Based on your experience, is each of the following...Ch. 1 - Calculate the grams of sugar present in a 355 mL...Ch. 1 - Calculate the density in g/mL of 2.0 L of gasoline...Ch. 1 - Prob. 1.31PPCh. 1 - A liquid has a mass of 54.5 g and a volume of 50.0...Ch. 1 - A family visiting Europe goes to the hospital...Ch. 1 - Fetal cord blood is stored at 112 F. Calculate...Ch. 1 - Prob. 1.35PPCh. 1 - Prob. 1.36PPCh. 1 - A defibrillator delivers about 360 joules per...Ch. 1 - Prob. 1.38PPCh. 1 - Two warehouses have space available for storage....Ch. 1 - Prob. 1.40PPCh. 1 - Indicate if each of the following describes a...Ch. 1 - Indicate if each of the following describes a...Ch. 1 - Prob. 1.43PPCh. 1 - Consider the following measurements determined for...Ch. 1 - A low dose of aspirin is often recommended for...Ch. 1 - A mother is to give her child 10 ccs of medicine...Ch. 1 - Give Drug X 5 mg/kg per day in two divided doses....Ch. 1 - A 38-lb child is prescribed acyclovir for chicken...Ch. 1 - A patient gets 2.0 L of fluid over 18 hours...Ch. 1 - How long would it take in hours to administer...Ch. 1 - A tablet of Benadryl (R), an antihistamine, has a...Ch. 1 - A medium-sized carrot weighs 61 g and contains 6 g...Ch. 1 - Determine whether each of the following is a...Ch. 1 - Prob. 1.54PPCh. 1 - Prob. 1.55PPCh. 1 - Prob. 1.56PPCh. 1 - Add coefficients to balance the chemical equations...Ch. 1 - Add coefficients to balance the chemical equations...Ch. 1 - Classify each of the following as a mixture or a...Ch. 1 - For each of the substances that you classified as...Ch. 1 - Prob. 1.61APCh. 1 - Prob. 1.62APCh. 1 - For each of the substances that you classified as...Ch. 1 - Prob. 1.64APCh. 1 - Use the periodic table to supply the missing...Ch. 1 - Use the periodic table to supply the missing...Ch. 1 - Prob. 1.67APCh. 1 - Prob. 1.68APCh. 1 - Prob. 1.69APCh. 1 - Prob. 1.70APCh. 1 - Supply the missing information in each of the...Ch. 1 - Supply the mating information in each of the...Ch. 1 - Prob. 1.73APCh. 1 - Prob. 1.74APCh. 1 - Prob. 1.75APCh. 1 - If a drop of blood is 0.05 mL, how many drops of...Ch. 1 - If a prescription calls for 1.0 g of...Ch. 1 - Prob. 1.78APCh. 1 - Prob. 1.79APCh. 1 - Round the following numbers to two significant...Ch. 1 - Consider the following data set for three bags of...Ch. 1 - It is flu season. Professor F has a class with 50...Ch. 1 - Prob. 1.83APCh. 1 - An adult human femur weighs about 225 g and has a...Ch. 1 - The specific gravity of olive oil is 0.703. How...Ch. 1 - Prob. 1.86APCh. 1 - To keep a room comfortable, the air is heated or...Ch. 1 - On the Kelvin scale, the lower limit of the...Ch. 1 - Prob. 1.89APCh. 1 - Prob. 1.90APCh. 1 - A cup of yogurt contains 130 Calories. Calculate...Ch. 1 - Prob. 1.92APCh. 1 - Prob. 1.93APCh. 1 - Prob. 1.94APCh. 1 - Prob. 1.95APCh. 1 - Prob. 1.96APCh. 1 - Prob. 1.97APCh. 1 - Prob. 1.98APCh. 1 - A student is weighing a standard 5.00 g weight...Ch. 1 - Prob. 1.100APCh. 1 - A mother calls you to ask about a proper dosage of...Ch. 1 - A prescription for amoxicillin comes in an oral...Ch. 1 - A patient needs exactly 1000 mL of a fluid over a...Ch. 1 - Prob. 1.104APCh. 1 - How does the arrangement of particles in a liquid...Ch. 1 - Prob. 1.106APCh. 1 - Identify each of the following as a physical...Ch. 1 - Prob. 1.108APCh. 1 - Add coefficients to balance the chemical equations...Ch. 1 - Prob. 1.110APCh. 1 - If red spheres represent oxygen atoms and blue...Ch. 1 - Prob. 1.112APCh. 1 - To donate blood, your blood must have a density...Ch. 1 - Prob. 1.114CPCh. 1 - A physician orders a Heparin drip at 8.0 units per...Ch. 1 - The following equation shows the reaction of...Ch. 1 - Table sugar (C12H22O12) is completely dissolved in...Ch. 1 - We know high density lipoprotein (HDL) and low...Ch. 1 - Prob. 1IA.1QCh. 1 - Can an element be a pure substance? Can a compound...Ch. 1 - Using the information given, how might you define...Ch. 1 - Prob. 1IA.4QCh. 1 - Prob. 1IA.5QCh. 1 - Describe the difference between a homogeneous and...Ch. 1 - Would you classify the following matter as...Ch. 1 - What do you think the labels (s), (l), (g), and...Ch. 1 - Prob. 2IA.1QCh. 1 - Prob. 2IA.2QCh. 1 - Provide names for the following elements and...Ch. 1 - Prob. 2IA.4QCh. 1 - Prob. 2IA.5QCh. 1 - Are most of the elements on the periodic table...Ch. 1 - Prob. 1ICCh. 1 - Prob. 2ICCh. 1 - Find out how to read and interpret the results of...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- elow are experimentally determined van Deemter plots of column efficiency, H, vs. flow rate. H is a quantitative measurement of band broadening. The left plot is for a liquid chromatography application and the night is for gas chromatography. Compare and contrast these two plots in terms of the three band broadening mechanisms presented in this activity. How are they similar? How do they differ? Justify your answers.? 0.4 H (mm) 0.2 0.1- 0.3- 0 0.5 H (mm) 8.0 7.0 6.0 5.0 4.0- 3.0 T +++ 1.0 1.5 0 2.0 4.0 Flow Rate, u (cm/s) 6.0 8.0 Flow Rate, u (cm/s)arrow_forwardPredict the products of this organic reaction: + H ZH NaBH3CN H+ n. ? Click and drag to start drawing a structure. Xarrow_forwardWhat is the missing reactant R in this organic reaction? + R H3O+ + • Draw the structure of R in the drawing area below. • Be sure to use wedge and dash bonds if it's necessary to draw one particular enantiomer. Click and drag to start drawing a structure.arrow_forward
- What would be the best choices for the missing reagents 1 and 3 in this synthesis? 1 1. PPh3 2. n-BuLi 2 • Draw the missing reagents in the drawing area below. You can draw them in any arrangement you like. • Do not draw the missing reagent 2. If you draw 1 correctly, we'll know what it is. • Note: if one of your reagents needs to contain a halogen, use bromine. Click and drag to start drawing a structure.arrow_forwardThe product on the right-hand side of this reaction can be prepared from two organic reactants, under the conditions shown above and below the arrow. Draw 1 and 2 below, in any arrangement you like. 1+2 NaBH₂CN H+ N Click and drag to start drawing a structure. X $arrow_forwardExplain what is the maximum absorbance of in which caffeine absorbs?arrow_forward
- Explain reasons as to why the amount of caffeine extracted from both a singular extraction (5ml Mountain Dew) and a multiple extraction (2 x 5.0ml Mountain Dew) were severely high when compared to coca-cola?arrow_forwardProtecting Groups and Carbonyls 6) The synthesis generates allethrolone that exhibits high insect toxicity but low mammalian toxicity. They are used in pet shampoo, human lice shampoo, and industrial sprays for insects and mosquitos. Propose detailed mechanistic steps to generate the allethrolone label the different types of reagents (Grignard, acid/base protonation, acid/base deprotonation, reduction, oxidation, witting, aldol condensation, Robinson annulation, etc.) III + VI HS HS H+ CH,CH,Li III I II IV CI + P(Ph)3 V ༼ Hint: no strong base added VI S VII IX HO VIII -MgBr HgCl2,HgO HO. isomerization aqeuous solution H,SO, ༽༽༤༽༽ X MeOH Hint: enhances selectivity for reaction at the S X ☑arrow_forwardDraw the complete mechanism for the acid-catalyzed hydration of this alkene. esc 田 Explanation Check 1 888 Q A slock Add/Remove step Q F4 F5 F6 A བྲA F7 $ % 5 @ 4 2 3 & 6 87 Click and drag to start drawing a structure. © 2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Ce W E R T Y U S D LL G H IK DD 요 F8 F9 F10 F1 * ( 8 9 0 O P J K L Z X C V B N M H He commandarrow_forward
- Explanation Check F1 H₂O H₂ Pd 1) MCPBA 2) H3O+ 1) Hg(OAc)2, H₂O 2) NaBH4 OH CI OH OH OH hydration halohydrin formation addition halogenation hydrogenation inhalation hydrogenation hydration ☐ halohydrin formation addition halogenation formation chelation hydrogenation halohydrin formation substitution hydration halogenation addition Ohalohydrin formation subtraction halogenation addition hydrogenation hydration F2 80 F3 σ F4 F5 F6 1 ! 2 # 3 $ 4 % 05 Q W & Å © 2025 McGraw Hill LLC. All Rights Reserved. F7 F8 ( 6 7 8 9 LU E R T Y U A F9arrow_forwardShow the mechanism steps to obtain the lowerenergy intermediate: *see imagearrow_forwardSoap is made by the previous reaction *see image. The main difference between one soap and another soap isthe length (number of carbons) of the carboxylic acid. However, if a soap irritates your skin, they mostlikely used too much lye.Detergents have the same chemical structure as soaps except for the functional group. Detergentshave sulfate (R-SO4H) and phosphate (R-PO4H2) functional groups. Draw the above carboxylic acidcarbon chain but as the two variants of detergents. *see imagearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Chemistry: The Molecular ScienceChemistryISBN:9781285199047Author:John W. Moore, Conrad L. StanitskiPublisher:Cengage Learning
ChemistryChemistryISBN:9781305957404Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCostePublisher:Cengage Learning
Chemistry: Matter and ChangeChemistryISBN:9780078746376Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl WistromPublisher:Glencoe/McGraw-Hill School Pub Co
Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage Learning
Chemistry for Engineering StudentsChemistryISBN:9781337398909Author:Lawrence S. Brown, Tom HolmePublisher:Cengage Learning
Chemistry: The Molecular Science
Chemistry
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:Cengage Learning
Chemistry
Chemistry
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning
Chemistry: Matter and Change
Chemistry
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Glencoe/McGraw-Hill School Pub Co
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
Chemistry for Engineering Students
Chemistry
ISBN:9781337398909
Author:Lawrence S. Brown, Tom Holme
Publisher:Cengage Learning
Measurement and Significant Figures; Author: Professor Dave Explains;https://www.youtube.com/watch?v=Gn97hpEkTiM;License: Standard YouTube License, CC-BY
Trigonometry: Radians & Degrees (Section 3.2); Author: Math TV with Professor V;https://www.youtube.com/watch?v=U5a9e1J_V1Y;License: Standard YouTube License, CC-BY