You have the following sequence reads from a genomic clone of the Homo sapiens genome: Read 1: ATGCGATCTGTGAGCCGAGTCTTTA Read 2: AACAAAAATGTTGTTATTTTTATTTCAGATG Read 3: TTCAGATGCGATCTGTGAGCCGAG Read 4: TGTCTGCCATTCTTAAAAACAAAAATGT Read 5: TGTTATTTTTATTTCAGATGCGA Read 6: AACAAAAATGTTGTTATT a. Use these six sequence reads to create a sequence contig of this part of the H. sapiens genome. b. Translate the sequence contig in all possible reading frames. c. Go to the BLAST page of the National Center for Biotechnology Information, or NCBI (http://www.ncbi .nlm.nih.gov/BLAST/, Appendix B) and see if you can identify the gene of which this sequence is a part by using each of the reading frames as a query for protein– protein comparison (BLASTp).

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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You have the following sequence reads from a genomic
clone of the Homo sapiens genome:
Read 1: ATGCGATCTGTGAGCCGAGTCTTTA
Read 2: AACAAAAATGTTGTTATTTTTATTTCAGATG
Read 3: TTCAGATGCGATCTGTGAGCCGAG
Read 4: TGTCTGCCATTCTTAAAAACAAAAATGT
Read 5: TGTTATTTTTATTTCAGATGCGA
Read 6: AACAAAAATGTTGTTATT
a. Use these six sequence reads to create a sequence
contig of this part of the H. sapiens genome.
b. Translate the sequence contig in all possible reading
frames.
c. Go to the BLAST page of the National Center for
Biotechnology Information, or NCBI (http://www.ncbi
.nlm.nih.gov/BLAST/, Appendix B) and see if you can
identify the gene of which this sequence is a part by
using each of the reading frames as a query for protein–
protein comparison (BLASTp).

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